UPBUpstream Bio, Inc.Healthcare · Biotechnologyas of 2026-08-13
Horizon

Issued 2026-08-13 at $6.91 · now $6.91 (2026-08-13, +0.0% since)

Based on its own history, a month from the 2026-08-13 close, UPB has typically landed between $4.28 and $9.44 — a range of −38.1% to +36.6% from the issuance price $6.91.

Range of outcomes in historically similar periods — not a price prediction. Ranges are scored publicly on /methodology.
  • Actual close
  • Typical path (median)
  • Middle 50% of outcomes
  • 90% range

439 overlapping 1 month windows · 2024-10-112026-07-15 · basis climatology · forecast (batch). Probability up 53.8% (90% CI 51.656.0%, ≈1,400 obs).

The cone is anchored at the 2026-08-13 issuance close ($6.91) — the price the forecast resolves against on 2026-09-11, not the latest close. The drawn path shape is illustrative (bands widen with √t); every labeled number is real — the anchor, the scored batch p90/IQR endpoints, and the typical move.

Where UPB has typically landed a month from the 2026-08-13 close of $6.91 — the range is history, not a prediction.

$4.28worst · -38.1%$9.44best · +36.6%
  • now $6.91 (+0.0%)
  • typicalThe typical outcome — half of similar past periods did better and half did worse (not an average, so a few wild periods don't skew it). $7.06 (+2.2%)
  • middle 50%The central range of outcomes — half of similar past periods landed inside it, a quarter finished above, a quarter below. $5.82$8.31
  • 90% rangeA nine-in-ten range — in about nine of every ten similar past periods the outcome stayed within these bounds. $4.28$9.44
Actual 1-month windows behind the coneiEvery overlapping 1-month window in this security's own price history was ranked by realized return; shown are the 3 worst and 3 best of 439 windows spanning 2024-10-11 to 2026-08-13. Not cherry-picked — these are the extremes of the full sample. Max drop / max rise are the deepest and highest points reached within each window. See /methodology.
StartReturnMax dropMax rise
3 worst
2026-01-30−76.3%−76.3%+0.0%
2026-01-27−75.7%−76.2%+0.0%
2026-01-29−75.1%−75.2%+0.5%
3 best
2025-07-17+71.5%−3.6%+71.5%
2025-07-16+70.5%−2.6%+70.5%
2025-07-18+68.1%−0.7%+76.6%

439 overlapping windows · 2024-10-112026-08-13 · not cherry-picked

Pending catalysts

  • September 2027Trial primary completion: Phase 2 primary completion: A Long-Term Safety and Efficacy Study of Verekitug (UPB-101) in Adult Participants With Severe Asthma (VALOUR) (source, as of 2026-08-14)
  • October 2027Trial primary completion: Phase 2 primary completion: A Study to Assess the Efficacy and Safety of Verekitug in Participants With COPD (source, as of 2026-08-14)

Public, scheduled events — dated attention, not a prediction of the outcome. See the FDA catalysts page for the historical base rate.

Seasonality · by month iHow this security has tended to do in each calendar month historically — a frequency, never a prediction.

iFor each calendar month, the share of years this security closed higher than the month before, and the average month-over-month return, over ~2 years of its own price history. Cells are shaded by average return. This is historical frequency, not a prediction — no month is a signal.
Jan
50%
−10.0%
n=2
Feb
0%
−50.8%
n=2
Mar
50%
−2.8%
n=2
Apr
100%
+26.7%
n=2
May
0%
−4.6%
n=2
Jun
50%
+0.9%
n=2
Jul
50%
+15.3%
n=2
Aug
100%
+10.7%
n=2
Sep
100%
+9.8%
n=1
Oct
100%
+37.4%
n=1
Nov
50%
−0.6%
n=2
Dec
0%
−14.9%
n=2

Up-frequency and average month-over-month return · historical frequency, not a prediction

Company insiders iOpen-market share purchases and sales by the company's own officers and directors, by filing date.

Last 90 days · as of 2026-08-13 · point-in-time by filing date

No insider transactions on record in the last 90 days.

Congressional disclosures

No congressional trades disclosed for this company.

Research tool, not investment advice — historical frequencies, not recommendations. Full terms.