Issued 2026-09-25 at $111.95 · now $111.95 (2026-09-25, +0.0% since)
Based on its own history, a month from the 2026-09-25 close, KYMR has typically landed between $85.90 and $162.21 — a range of −23.3% to +44.9% from the issuance price $111.95.
- Actual close
- Typical path (median)
- Middle 50% of outcomes
- 90% range
1,510 overlapping 1 month windows · 2020-08-21 – 2026-08-26 · basis climatology · forecast (batch). Base rate up 53.7% (90% CI 51.5–55.9%, ≈1,391 obs). Not a call on this stock — we have no evidence its odds differ.
The cone is anchored at the 2026-09-25 issuance close ($111.95) — the price the forecast resolves against on 2026-10-26, not the latest close. The drawn path shape is illustrative (bands widen with √t); every labeled number is real — the anchor, the scored batch p90/IQR endpoints, and the typical move.
Where KYMR has typically landed a month from the 2026-09-25 close of $111.95 — the range is history, not a prediction.
- now $111.95 (+0.0%)
- typicalThe typical outcome — half of similar past periods did better and half did worse (not an average, so a few wild periods don't skew it). $110.92 (-0.9%)
- middle 50%The central range of outcomes — half of similar past periods landed inside it, a quarter finished above, a quarter below. $96.05–$125.79
- 90% rangeA nine-in-ten range — in about nine of every ten similar past periods the outcome stayed within these bounds. $85.9–$162.21
Actual 1-month windows behind the coneiEvery overlapping 1-month window in this security's own price history was ranked by realized return; shown are the 3 worst and 3 best of 1,510 windows spanning 2020-08-21 to 2026-09-25. Not cherry-picked — these are the extremes of the full sample. Max drop / max rise are the deepest and highest points reached within each window. See /methodology.
| Start | Return | Max drop | Max rise |
|---|---|---|---|
| 3 worst | |||
| 2022-04-20 | −59.7% | −59.7% | +0.0% |
| 2022-04-25 | −58.9% | −58.9% | +0.0% |
| 2022-04-19 | −58.1% | −58.1% | +0.0% |
| 3 best | |||
| 2020-11-24 | +88.0% | +0.0% | +88.0% |
| 2020-11-25 | +86.1% | −1.2% | +86.1% |
| 2023-10-27 | +83.5% | +0.0% | +90.4% |
1,510 overlapping windows · 2020-08-21 – 2026-09-25 · not cherry-picked
Pending catalysts
- June 2027 — Trial primary completion: Phase 2 primary completion: A Study of KT-621 Administered Orally to Participants With Moderate to Severe Atopic Dermatitis (source, as of 2026-08-14)
- December 2027 — Trial primary completion: Phase 2 primary completion: A Study of KT-621 Administered Orally to Adult Participants With Moderate to Severe Eosinophilic Asthma (source, as of 2026-08-14)
- December 2028 — Trial primary completion: Phase 2 primary completion: A Long-term Study of KT-621 Administered Orally to Participants With Asthma Previously Enrolled in a KT-621 Asthma Study (source, as of 2026-08-14)
Public, scheduled events — dated attention, not a prediction of the outcome. See the FDA catalysts page for the historical base rate.
Seasonality · by month iHow this security has tended to do in each calendar month historically — a frequency, never a prediction.
iFor each calendar month, the share of years this security closed higher than the month before, and the average month-over-month return, over ~7 years of its own price history. Cells are shaded by average return. This is historical frequency, not a prediction — no month is a signal.Jan
33%
+6.1%
n=6
Feb
33%
−1.5%
n=6
Mar
17%
−7.6%
n=6
Apr
50%
+0.7%
n=6
May
33%
−12.2%
n=6
Jun
67%
+16.3%
n=6
Jul
67%
+12.7%
n=6
Aug
67%
+5.4%
n=6
Sep
29%
−3.6%
n=7
Oct
67%
+7.0%
n=6
Nov
67%
+18.1%
n=6
Dec
67%
+9.4%
n=6
Up-frequency and average month-over-month return · historical frequency, not a prediction
Reported insider & political trades
Every Form 4 the people closest to this company have filed with the SEC — plotted against the share price, aggregated by month, and shown with the gap between when each trade happened and when it was disclosed. A public record, not advice.
| Date | Person | Role | Action | Shares @ price | Value | Ownership Δ | vs S&P 1m | vs S&P 6m | Owned after | Filing |
|---|---|---|---|---|---|---|---|---|---|---|
| 2026-09-04 | Adams Brian | officer | Sale | 3,025 @ $116.81 | $353K | −5.5% of holding | not yet — horizon still open | not yet — horizon still open | 52,391 | Form 4 · filed same day |
| 2026-09-04 | Adams Brian | officer | Sale | 2,137 @ $117.57 | $251K | −4.1% of holding | not yet — horizon still open | not yet — horizon still open | 50,254 | Form 4 · filed same day |
| 2026-09-04 | Adams Brian | officer | Sale | 1,209 @ $115.55 | $140K | −2.1% of holding | not yet — horizon still open | not yet — horizon still open | 55,416 | Form 4 · filed same day |
| 2026-07-07 | Mainolfi Nello | director | Sale | 50,000 @ $119.00 | $6.0M | −7.0% of holding | −14.5% | not yet — horizon still open | 666,568 | Form 4 · filed same day |
| 2026-07-01 | Mainolfi Nello | director | Sale | 44,050 @ $115.69 | $5.1M | −6.2% of holding | −9.6% | not yet — horizon still open | 669,904 | Form 4 · filed 1 day after the trade |
| 2026-07-01 | Mainolfi Nello | director | Sale | 24,105 @ $114.96 | $2.8M | −3.3% of holding | −9.6% | not yet — horizon still open | 713,954 | Form 4 · filed 1 day after the trade |
| 2026-07-01 | Mainolfi Nello | director | Sale | 6,626 @ $113.98 | $755K | −0.9% of holding | −9.6% | not yet — horizon still open | 738,059 | Form 4 · filed 1 day after the trade |
| 2026-07-01 | Mainolfi Nello | director | Sale | 3,336 @ $116.56 | $389K | −0.5% of holding | −9.6% | not yet — horizon still open | 666,568 | Form 4 · filed 1 day after the trade |
| 2026-07-01 | Goodman Noah | officer | Sale | 3,389 @ $114.29 | $387K | −6.7% of holding | −9.6% | not yet — horizon still open | 47,179 | Form 4 · filed 1 day after the trade |
| 2026-07-01 | Mainolfi Nello | director | Sale | 1,883 @ $112.80 | $212K | −0.3% of holding | −9.6% | not yet — horizon still open | 744,685 | Form 4 · filed 1 day after the trade |
| 2026-06-30 | Jacobs Bruce N. | officer | Sale | 51,375 @ $114.77 | $5.9M | −16.4% of holding | −6.0% | not yet — horizon still open | 262,207 | Form 4 · filed 2 days after the trade |
| 2026-06-30 | Jacobs Bruce N. | officer | Sale | 7,971 @ $115.82 | $923K | −3.0% of holding | −6.0% | not yet — horizon still open | 254,236 | Form 4 · filed 2 days after the trade |
| 2026-06-30 | Jacobs Bruce N. | officer | Sale | 6,153 @ $116.99 | $720K | −2.4% of holding | −6.0% | not yet — horizon still open | 248,083 | Form 4 · filed 2 days after the trade |
| 2026-06-30 | Jacobs Bruce N. | officer | Sale | 4,110 @ $114.19 | $469K | −1.3% of holding | −6.0% | not yet — horizon still open | 313,582 | Form 4 · filed 2 days after the trade |
| 2026-06-30 | Jacobs Bruce N. | officer | Sale | 3,200 @ $117.70 | $377K | −1.3% of holding | −6.0% | not yet — horizon still open | 244,883 | Form 4 · filed 2 days after the trade |
| 2026-06-30 | Jacobs Bruce N. | officer | Sale | 1,700 @ $111.57 | $190K | −0.5% of holding | −6.0% | not yet — horizon still open | 318,792 | Form 4 · filed 2 days after the trade |
| 2026-06-30 | Jacobs Bruce N. | officer | Sale | 1,500 @ $110.54 | $166K | −0.5% of holding | −6.0% | not yet — horizon still open | 320,492 | Form 4 · filed 2 days after the trade |
| 2026-06-30 | Jacobs Bruce N. | officer | Sale | 1,100 @ $112.79 | $124K | −0.3% of holding | −6.0% | not yet — horizon still open | 317,692 | Form 4 · filed 2 days after the trade |
| 2026-06-29 | Booth Bruce | director | Sale | 19,093 @ $107.76 | $2.1M | −0.8% of holding | −2.2% | not yet — horizon still open | 2,412,747 | Form 4 · filed 1 day after the trade |
| 2026-06-29 | Booth Bruce | director | Sale | 14,613 @ $106.63 | $1.6M | −0.6% of holding | −2.2% | not yet — horizon still open | 2,431,840 | Form 4 · filed 1 day after the trade |
| 2026-06-29 | Booth Bruce | director | Sale | 10,658 @ $108.28 | $1.2M | −0.4% of holding | −2.2% | not yet — horizon still open | 2,402,089 | Form 4 · filed 1 day after the trade |
| 2026-06-29 | Booth Bruce | director | Sale | 7,833 @ $109.75 | $860K | −0.3% of holding | −2.2% | not yet — horizon still open | 2,394,256 | Form 4 · filed 1 day after the trade |
| 2026-06-29 | Booth Bruce | director | Sale | 7,602 @ $110.67 | $841K | −0.3% of holding | −2.2% | not yet — horizon still open | 2,386,654 | Form 4 · filed 1 day after the trade |
| 2026-06-29 | Booth Bruce | director | Sale | 5,471 @ $105.78 | $579K | −0.2% of holding | −2.2% | not yet — horizon still open | 2,446,453 | Form 4 · filed 1 day after the trade |
| 2026-06-29 | Booth Bruce | director | Sale | 3,024 @ $107.76 | $326K | −0.6% of holding | −2.2% | not yet — horizon still open | 466,077 | Form 4 · filed 1 day after the trade |
| 2026-06-29 | Booth Bruce | director | Sale | 2,318 @ $106.63 | $247K | −0.5% of holding | −2.2% | not yet — horizon still open | 469,101 | Form 4 · filed 1 day after the trade |
| 2026-06-29 | Booth Bruce | director | Sale | 1,688 @ $108.28 | $183K | −0.4% of holding | −2.2% | not yet — horizon still open | 464,389 | Form 4 · filed 1 day after the trade |
| 2026-06-29 | Booth Bruce | director | Sale | 1,239 @ $109.75 | $136K | −0.3% of holding | −2.2% | not yet — horizon still open | 463,150 | Form 4 · filed 1 day after the trade |
| 2026-06-29 | Booth Bruce | director | Sale | 1,199 @ $110.67 | $133K | −0.3% of holding | −2.2% | not yet — horizon still open | 461,951 | Form 4 · filed 1 day after the trade |
| 2026-06-29 | Booth Bruce | director | Sale | 907 @ $111.20 | $101K | −0.0% of holding | −2.2% | not yet — horizon still open | 2,385,747 | Form 4 · filed 1 day after the trade |
| 2026-06-29 | Booth Bruce | director | Sale | 848 @ $105.78 | $90K | −0.2% of holding | −2.2% | not yet — horizon still open | 471,419 | Form 4 · filed 1 day after the trade |
| 2026-06-29 | Booth Bruce | director | Sale | 157 @ $111.20 | $17K | −0.0% of holding | −2.2% | not yet — horizon still open | 461,794 | Form 4 · filed 1 day after the trade |
| 2026-06-26 | BVF PARTNERS L P/IL | director | Sale | 837,914 @ $106.50 | $89.2M | −29.9% of holding | −3.4% | not yet — horizon still open | 1,960,881 | Form 4 · filed same day |
| 2026-06-26 | BVF PARTNERS L P/IL | director | Sale | 627,597 @ $106.50 | $66.8M | −28.3% of holding | −3.4% | not yet — horizon still open | 1,592,261 | Form 4 · filed same day |
| 2026-06-26 | Booth Bruce | director | Sale | 231,007 @ $108.14 | $25.0M | −8.2% of holding | −3.4% | not yet — horizon still open | 2,603,048 | Form 4 · filed 4 days after the trade |
| 2026-06-26 | BVF PARTNERS L P/IL | director | Sale | 113,289 @ $106.50 | $12.1M | −32.1% of holding | −3.4% | not yet — horizon still open | 240,123 | Form 4 · filed same day |
| 2026-06-26 | BVF PARTNERS L P/IL | director | Sale | 51,858 @ $106.50 | $5.5M | −39.7% of holding | −3.4% | not yet — horizon still open | 78,787 | Form 4 · filed same day |
| 2026-06-26 | Booth Bruce | director | Sale | 32,624 @ $109.79 | $3.6M | −1.3% of holding | −3.4% | not yet — horizon still open | 2,570,424 | Form 4 · filed 4 days after the trade |
| 2026-06-26 | Booth Bruce | director | Sale | 32,402 @ $108.14 | $3.5M | −6.2% of holding | −3.4% | not yet — horizon still open | 493,358 | Form 4 · filed 4 days after the trade |
| 2026-06-26 | Booth Bruce | director | Sale | 27,951 @ $114.94 | $3.2M | −1.1% of holding | −3.4% | not yet — horizon still open | 2,505,362 | Form 4 · filed 4 days after the trade |
| 2026-06-26 | Booth Bruce | director | Sale | 28,296 @ $107.57 | $3.0M | −1.0% of holding | −3.4% | not yet — horizon still open | 2,834,055 | Form 4 · filed 4 days after the trade |
| 2026-06-26 | Booth Bruce | director | Sale | 22,046 @ $117.85 | $2.6M | −0.9% of holding | −3.4% | not yet — horizon still open | 2,464,314 | Form 4 · filed 4 days after the trade |
| 2026-06-26 | Booth Bruce | director | Sale | 14,913 @ $113.97 | $1.7M | −0.6% of holding | −3.4% | not yet — horizon still open | 2,533,313 | Form 4 · filed 4 days after the trade |
| 2026-06-26 | Booth Bruce | director | Sale | 12,390 @ $118.66 | $1.5M | −0.5% of holding | −3.4% | not yet — horizon still open | 2,451,924 | Form 4 · filed 4 days after the trade |
| 2026-06-26 | Booth Bruce | director | Sale | 12,181 @ $117.09 | $1.4M | −0.5% of holding | −3.4% | not yet — horizon still open | 2,486,360 | Form 4 · filed 4 days after the trade |
| 2026-06-26 | Booth Bruce | director | Sale | 11,277 @ $110.49 | $1.2M | −0.4% of holding | −3.4% | not yet — horizon still open | 2,559,147 | Form 4 · filed 4 days after the trade |
| 2026-06-26 | Booth Bruce | director | Sale | 10,366 @ $111.51 | $1.2M | −0.4% of holding | −3.4% | not yet — horizon still open | 2,548,781 | Form 4 · filed 4 days after the trade |
| 2026-06-26 | Booth Bruce | director | Sale | 6,821 @ $115.69 | $789K | −0.3% of holding | −3.4% | not yet — horizon still open | 2,498,541 | Form 4 · filed 4 days after the trade |
| 2026-06-26 | Booth Bruce | director | Sale | 4,562 @ $109.79 | $501K | −0.9% of holding | −3.4% | not yet — horizon still open | 488,796 | Form 4 · filed 4 days after the trade |
| 2026-06-26 | Booth Bruce | director | Sale | 3,896 @ $114.94 | $448K | −0.8% of holding | −3.4% | not yet — horizon still open | 479,718 | Form 4 · filed 4 days after the trade |
| 2026-06-26 | Booth Bruce | director | Sale | 3,958 @ $107.57 | $426K | −0.7% of holding | −3.4% | not yet — horizon still open | 525,760 | Form 4 · filed 4 days after the trade |
| 2026-06-26 | Booth Bruce | director | Sale | 3,069 @ $117.85 | $362K | −0.6% of holding | −3.4% | not yet — horizon still open | 473,996 | Form 4 · filed 4 days after the trade |
| 2026-06-26 | Booth Bruce | director | Sale | 2,083 @ $113.97 | $237K | −0.4% of holding | −3.4% | not yet — horizon still open | 483,614 | Form 4 · filed 4 days after the trade |
| 2026-06-26 | Booth Bruce | director | Sale | 1,729 @ $118.66 | $205K | −0.4% of holding | −3.4% | not yet — horizon still open | 472,267 | Form 4 · filed 4 days after the trade |
| 2026-06-26 | Booth Bruce | director | Sale | 1,701 @ $117.09 | $199K | −0.4% of holding | −3.4% | not yet — horizon still open | 477,065 | Form 4 · filed 4 days after the trade |
| 2026-06-26 | Booth Bruce | director | Sale | 1,579 @ $110.49 | $174K | −0.3% of holding | −3.4% | not yet — horizon still open | 487,217 | Form 4 · filed 4 days after the trade |
| 2026-06-26 | Booth Bruce | director | Sale | 1,442 @ $111.51 | $161K | −0.3% of holding | −3.4% | not yet — horizon still open | 485,775 | Form 4 · filed 4 days after the trade |
| 2026-06-26 | Booth Bruce | director | Sale | 952 @ $115.69 | $110K | −0.2% of holding | −3.4% | not yet — horizon still open | 478,766 | Form 4 · filed 4 days after the trade |
| 2026-06-26 | Booth Bruce | director | Sale | 555 @ $112.49 | $62K | −0.0% of holding | −3.4% | not yet — horizon still open | 2,548,226 | Form 4 · filed 4 days after the trade |
| 2026-06-26 | Booth Bruce | director | Sale | 78 @ $112.49 | $9K | −0.0% of holding | −3.4% | not yet — horizon still open | 485,697 | Form 4 · filed 4 days after the trade |
The vs-S&P columns are a labeled look-back on what the stock did after each filing, measured against the index over the same window. Descriptive history, not a claim about the person or a reason to trade.
81 award / exercise / gift records — not counted as purchases
Awards, option exercises, gifts and tax-withholding disposals are shown separately and never counted as open-market purchases or sales — they carry no conviction information.
| Date | Person | Role | Action | Shares | Owned after | Filing |
|---|---|---|---|---|---|---|
| 2026-07-27 | Rooney Terence | officer | Award / grant | 38,000 | 38,000 | Form 4 |
| 2026-07-27 | Rooney Terence | officer | Award / grant | 76,000 | 76,000 | Form 4 |
| 2026-07-07 | Mainolfi Nello | director | Option exercise | 50,000 | 716,568 | Form 4 |
| 2026-07-07 | Mainolfi Nello | director | Option exercise | 45,559 | 90,000 | Form 4 |
| 2026-07-07 | Mainolfi Nello | director | Option exercise | 4,441 | 14,284 | Form 4 |
| 2026-07-01 | Mainolfi Nello | director | Option exercise | 80,000 | 746,568 | Form 4 |
| 2026-07-01 | Mainolfi Nello | director | Option exercise | 80,000 | 135,559 | Form 4 |
| 2026-06-30 | Jacobs Bruce N. | officer | Option exercise | 61,378 | 321,992 | Form 4 |
| 2026-06-30 | Jacobs Bruce N. | officer | Option exercise | 61,378 | 0 | Form 4 |
| 2026-06-25 | Goodman Noah | officer | Option exercise | 5,000 | 55,195 | Form 4 |
| 2026-06-25 | Goodman Noah | officer | Option exercise | 5,000 | 90,000 | Form 4 |
| 2026-06-24 | Sandor Victor | director | Award / grant | 6,068 | 6,068 | Form 4 |
| 2026-06-24 | Esposito Pamela | director | Award / grant | 6,068 | 6,068 | Form 4 |
| 2026-06-24 | Hrustanovic Gorjan | director | Award / grant | 6,068 | 6,068 | Form 4 |
| 2026-06-24 | MARAGANORE JOHN | director | Award / grant | 6,068 | 6,068 | Form 4 |
| 2026-06-24 | Ridloff Elena | director | Award / grant | 6,068 | 6,068 | Form 4 |
| 2026-06-24 | Booth Bruce | director | Award / grant | 6,068 | 6,068 | Form 4 |
| 2026-06-24 | BVF PARTNERS L P/IL | director | Award / grant | 6,068 | 6,068 | Form 4 |
| 2026-06-24 | Albers Jeffrey W. | director | Award / grant | 6,068 | 6,068 | Form 4 |
| 2026-06-24 | BAKER BROS. ADVISORS LP | director | Award / grant | 6,068 | 6,068 | Form 4 |
| 2026-06-22 | Goodman Noah | officer | Option exercise | 2,500 | 52,695 | Form 4 |
| 2026-06-22 | Goodman Noah | officer | Option exercise | 2,500 | 95,000 | Form 4 |
| 2026-06-17 | Booth Bruce | director | Option exercise | 11,741 | 11,741 | Form 4 |
| 2026-06-17 | Booth Bruce | director | Option exercise | 11,741 | 28,127 | Form 4 |
| 2026-06-02 | Jacobs Bruce N. | officer | Option exercise | 12,653 | 260,241 | Form 4 |
| 2026-06-02 | Jacobs Bruce N. | officer | Option exercise | 12,653 | 0 | Form 4 |
| 2026-05-19 | Esposito Pamela | director | Option exercise | 1,000 | 1,000 | Form 4 |
| 2026-05-19 | Esposito Pamela | director | Option exercise | 1,000 | 9,000 | Form 4 |
| 2026-05-18 | Jacobs Bruce N. | officer | Option exercise | 15,000 | 247,588 | Form 4 |
| 2026-05-18 | Jacobs Bruce N. | officer | Option exercise | 15,000 | 12,653 | Form 4 |
| 2026-05-11 | Ridloff Elena | director | Option exercise | 3,000 | 3,000 | Form 4 |
| 2026-05-11 | Ridloff Elena | director | Option exercise | 3,000 | 13,000 | Form 4 |
| 2026-04-29 | Mainolfi Nello | director | Option exercise | 30,000 | 696,195 | Form 4 |
| 2026-04-29 | Mainolfi Nello | director | Option exercise | 30,000 | 215,559 | Form 4 |
| 2026-04-22 | Booth Bruce | director | Option exercise | 5,641 | 5,641 | Form 4 |
| 2026-04-22 | Chadwick Jeremy G | officer | Option exercise | 200 | 61,502 | Form 4 |
| 2026-04-22 | Booth Bruce | director | Option exercise | 259 | 5,900 | Form 4 |
| 2026-04-22 | Chadwick Jeremy G | officer | Option exercise | 100 | 61,302 | Form 4 |
| 2026-04-22 | Booth Bruce | director | Option exercise | 259 | 39,868 | Form 4 |
| 2026-04-22 | Booth Bruce | director | Option exercise | 5,641 | 0 | Form 4 |
Source: SEC Form 4 filings. Each row links to its original filing.
Across 2012–2021, stocks where a CEO, C-suite officer, or director had recently made an open-market common-stock purchase ran about +28 bp per month above the universe average (n=34,268 stock-weeks). A historical tendency, not a prediction.
Congressional disclosures
No congressional trades disclosed for this company.
Research tool, not investment advice — historical frequencies, not recommendations. A product of Marovel Technologies LLC. Full terms.