EWTXEdgewise Therapeutics, Inc.Healthcare · Biotechnologyas of 2026-09-25
Horizon

Issued 2026-09-25 at $39.34 · now $39.34 (2026-09-25, +0.0% since)

Based on its own history, a month from the 2026-09-25 close, EWTX has typically landed between $29.62 and $55.62 — a range of −24.7% to +41.4% from the issuance price $39.34.

Range of outcomes in historically similar periods — not a price prediction. Ranges are scored publicly on /methodology.
  • Actual close
  • Typical path (median)
  • Middle 50% of outcomes
  • 90% range

1,361 overlapping 1 month windows · 2021-03-26 – 2026-08-26 · basis climatology · forecast (batch). Base rate up 53.7% (90% CI 51.5–55.9%, ≈1,391 obs). Not a call on this stock — we have no evidence its odds differ.

The cone is anchored at the 2026-09-25 issuance close ($39.34) — the price the forecast resolves against on 2026-10-26, not the latest close. The drawn path shape is illustrative (bands widen with √t); every labeled number is real — the anchor, the scored batch p90/IQR endpoints, and the typical move.

Where EWTX has typically landed a month from the 2026-09-25 close of $39.34 — the range is history, not a prediction.

$29.62worst · -24.7%$55.62best · +41.4%
  • now $39.34 (+0.0%)
  • typicalThe typical outcome — half of similar past periods did better and half did worse (not an average, so a few wild periods don't skew it). $39.43 (+0.2%)
  • middle 50%The central range of outcomes — half of similar past periods landed inside it, a quarter finished above, a quarter below. $35.07–$43.79
  • 90% rangeA nine-in-ten range — in about nine of every ten similar past periods the outcome stayed within these bounds. $29.62–$55.62
Actual 1-month windows behind the coneiEvery overlapping 1-month window in this security's own price history was ranked by realized return; shown are the 3 worst and 3 best of 1,361 windows spanning 2021-03-26 to 2026-09-25. Not cherry-picked — these are the extremes of the full sample. Max drop / max rise are the deepest and highest points reached within each window. See /methodology.
StartReturnMax dropMax rise
3 worst
2025-03-06−59.1%−59.1%+0.0%
2025-03-10−58.3%−58.3%+0.0%
2025-03-07−57.8%−58.9%+0.0%
3 best
2024-01-11+104.9%+0.0%+115.9%
2024-09-16+95.7%+0.0%+95.7%
2023-11-27+94.8%−3.5%+94.8%

1,361 overlapping windows · 2021-03-26 – 2026-09-25 · not cherry-picked

Pending catalysts

  • January 2027 — Trial primary completion: Phase 2 primary completion: A Study of EDG-5506 in Children With Duchenne Muscular Dystrophy (LYNX) (source, as of 2026-08-14)
  • March 2027 — Trial primary completion: Phase 2 primary completion: Phase 2 Study of EDG-5506 in Children and Adolescents With Duchenne Muscular Dystrophy Previously Treated With Gene Therapy (source, as of 2026-08-14)
  • December 2027 — Trial primary completion: Phase 2 primary completion: A Study of EDG-7500 in Adults With Hypertrophic Cardiomyopathy (CIRRUS-HCM) (source, as of 2026-08-14)
  • February 2031 — Trial primary completion: Phase 2 primary completion: Open-Label Extension of EDG-5506 in Participants With Becker Muscular Dystrophy (source, as of 2026-08-14)

Public, scheduled events — dated attention, not a prediction of the outcome. See the FDA catalysts page for the historical base rate.

Seasonality · by month iHow this security has tended to do in each calendar month historically — a frequency, never a prediction.

iFor each calendar month, the share of years this security closed higher than the month before, and the average month-over-month return, over ~6 years of its own price history. Cells are shaded by average return. This is historical frequency, not a prediction — no month is a signal.
Jan
80%
+17.0%
n=5
Feb
20%
−5.3%
n=5
Mar
40%
−9.8%
n=5
Apr
17%
−4.5%
n=6
May
50%
−2.1%
n=6
Jun
50%
−1.0%
n=6
Jul
33%
−0.7%
n=6
Aug
67%
−0.0%
n=6
Sep
50%
+7.3%
n=6
Oct
60%
+9.2%
n=5
Nov
40%
+7.1%
n=5
Dec
20%
+8.8%
n=5

Up-frequency and average month-over-month return · historical frequency, not a prediction

Reported insider & political trades

Every Form 4 the people closest to this company have filed with the SEC — plotted against the share price, aggregated by month, and shown with the gap between when each trade happened and when it was disclosed. A public record, not advice.

Share price & reported tradesMonthly open-market valueReporting lag — trade date to filing date2026-092026-082026-072026-062026-052026-042026-032026-022026-012025-122025-112025-102025-092025-08$48$142026-08-13: 1 insider sale, $127K — Donovan Joanne M.2026-08-12: 18 insider sales, $1.8M — KOCH KEVIN, Russell Alan J, Donovan Joanne M., Derakhshan Behrad …2026-07-01: 2 insider sales, $7.9M — Russell Alan J …2026-05-05: 1 insider sale, $1.9M — Donovan Joanne M.2026-05-04: 1 insider sale, $164K — Donovan Joanne M.2026-04-01: 1 insider sale, $926K — Donovan Joanne M.2026-03-31: 1 insider sale, $685K — Donovan Joanne M.2026-03-27: 2 insider sales, $507K — Donovan Joanne M. …2026-01-21: 5 insider sales, $3.4M — Edris Badreddin …2025-11-12: 1 insider sale, $2.1M — Russell Alan J2025-11-11: 1 insider purchase, $199K — Fox Jonathan C2025-08-26: 1 insider sale, $1.5M — Russell Alan J2025-08: 7 open-market sales, $1.7M2025-11: 1 open-market purchase, $199K2025-11: 1 open-market sale, $2.1M2026-01: 5 open-market sales, $3.4M2026-03: 3 open-market sales, $1.2M2026-04: 1 open-market sale, $926K2026-05: 2 open-market sales, $2.1M2026-07: 2 open-market sales, $7.9M2026-08: 19 open-market sales, $1.9M↑ buys↓ salesofficer Donovan Joanne M. — Sale on 2026-08-13, filed 1 day after the tradedirector KOCH KEVIN — Sale on 2026-08-12, filed 2 days after the tradedirector KOCH KEVIN — Sale on 2026-08-12, filed 2 days after the tradedirector Russell Alan J — Sale on 2026-08-12, filed 2 days after the tradeofficer Donovan Joanne M. — Sale on 2026-08-12, filed 2 days after the tradeofficer Donovan Joanne M. — Sale on 2026-08-12, filed 2 days after the tradeofficer Derakhshan Behrad — Sale on 2026-08-12, filed 2 days after the tradeofficer MOORE JOHN R — Sale on 2026-08-12, filed 2 days after the tradeofficer MOORE JOHN R — Sale on 2026-08-12, filed 2 days after the tradedirector Russell Alan J — Sale on 2026-08-12, filed 2 days after the tradeofficer Derakhshan Behrad — Sale on 2026-08-12, filed 2 days after the tradedirector KOCH KEVIN — Sale on 2026-08-12, filed 2 days after the tradeofficer Donovan Joanne M. — Sale on 2026-08-12, filed 2 days after the tradedirector Russell Alan J — Sale on 2026-08-12, filed 2 days after the tradeofficer Derakhshan Behrad — Sale on 2026-08-12, filed 2 days after the tradeofficer Derakhshan Behrad — Sale on 2026-08-12, filed 2 days after the tradeofficer Donovan Joanne M. — Sale on 2026-08-12, filed 2 days after the tradeofficer MOORE JOHN R — Sale on 2026-08-12, filed 2 days after the tradeofficer MOORE JOHN R — Sale on 2026-08-12, filed 2 days after the tradedirector Russell Alan J — Sale on 2026-07-01, filed 1 day after the tradedirector Russell Alan J — Sale on 2026-07-01, filed 1 day after the tradeofficer Donovan Joanne M. — Sale on 2026-05-05, filed same dayofficer Donovan Joanne M. — Sale on 2026-05-04, filed 1 day after the tradeofficer Donovan Joanne M. — Sale on 2026-04-01, filed 1 day after the tradeofficer Donovan Joanne M. — Sale on 2026-03-31, filed same dayofficer Donovan Joanne M. — Sale on 2026-03-27, filed 3 days after the tradeofficer Donovan Joanne M. — Sale on 2026-03-27, filed 3 days after the tradedirector Edris Badreddin — Sale on 2026-01-21, filed 2 days after the tradedirector Edris Badreddin — Sale on 2026-01-21, filed 2 days after the tradedirector Edris Badreddin — Sale on 2026-01-21, filed 2 days after the tradedirector Edris Badreddin — Sale on 2026-01-21, filed 2 days after the tradedirector Edris Badreddin — Sale on 2026-01-21, filed 2 days after the tradedirector Russell Alan J — Sale on 2025-11-12, filed 1 day after the tradedirector Fox Jonathan C — Purchase on 2025-11-11, filed 2 days after the tradedirector Russell Alan J — Sale on 2025-08-26, filed 2 days after the trade
DatePersonRoleActionShares @ priceValueOwnership Δvs S&P 1mvs S&P 6mOwned afterFiling
2026-08-13Donovan Joanne M.officerSale2,919 @ $43.41$127K−25.3% of holding+5.8%not yet — horizon still open8,625Form 4 · filed 1 day after the trade
2026-08-12KOCH KEVINdirectorSale8,782 @ $43.64$383K−12.5% of holding+3.0%not yet — horizon still open61,677Form 4 · filed 2 days after the trade
2026-08-12KOCH KEVINdirectorSale8,276 @ $43.66$361K−13.4% of holding+3.0%not yet — horizon still open53,401Form 4 · filed 2 days after the trade
2026-08-12Russell Alan JdirectorSale3,238 @ $43.68$141K−8.7% of holding+3.0%not yet — horizon still open34,129Form 4 · filed 2 days after the trade
2026-08-12Donovan Joanne M.officerSale2,839 @ $43.78$124K−15.7% of holding+3.0%not yet — horizon still open15,227Form 4 · filed 2 days after the trade
2026-08-12Donovan Joanne M.officerSale2,779 @ $43.71$121K−18.3% of holding+3.0%not yet — horizon still open12,448Form 4 · filed 2 days after the trade
2026-08-12Derakhshan BehradofficerSale2,475 @ $43.70$108K−7.2% of holding+3.0%not yet — horizon still open31,826Form 4 · filed 2 days after the trade
2026-08-12MOORE JOHN RofficerSale2,439 @ $43.81$107K−10.7% of holding+3.0%not yet — horizon still open20,274Form 4 · filed 2 days after the trade
2026-08-12MOORE JOHN RofficerSale2,419 @ $43.80$106K−12.0% of holding+3.0%not yet — horizon still open17,697Form 4 · filed 2 days after the trade
2026-08-12Russell Alan JdirectorSale2,273 @ $43.68$99K−6.7% of holding+3.0%not yet — horizon still open31,856Form 4 · filed 2 days after the trade
2026-08-12Derakhshan BehradofficerSale2,171 @ $43.79$95K−5.9% of holding+3.0%not yet — horizon still open34,755Form 4 · filed 2 days after the trade
2026-08-12KOCH KEVINdirectorSale913 @ $44.33$40K−1.7% of holding+3.0%not yet — horizon still open52,488Form 4 · filed 2 days after the trade
2026-08-12Donovan Joanne M.officerSale800 @ $44.52$36K−6.5% of holding+3.0%not yet — horizon still open11,544Form 4 · filed 2 days after the trade
2026-08-12Russell Alan JdirectorSale390 @ $44.46$17K−1.2% of holding+3.0%not yet — horizon still open31,466Form 4 · filed 2 days after the trade
2026-08-12Derakhshan BehradofficerSale304 @ $44.50$14K−0.9% of holding+3.0%not yet — horizon still open34,451Form 4 · filed 2 days after the trade
2026-08-12Derakhshan BehradofficerSale150 @ $44.44$7K−0.4% of holding+3.0%not yet — horizon still open34,301Form 4 · filed 2 days after the trade
2026-08-12Donovan Joanne M.officerSale104 @ $44.43$5K−0.8% of holding+3.0%not yet — horizon still open12,344Form 4 · filed 2 days after the trade
2026-08-12MOORE JOHN RofficerSale99 @ $44.50$4K−0.5% of holding+3.0%not yet — horizon still open20,116Form 4 · filed 2 days after the trade
2026-08-12MOORE JOHN RofficerSale59 @ $44.41$3K−0.3% of holding+3.0%not yet — horizon still open20,215Form 4 · filed 2 days after the trade
2026-07-01Russell Alan JdirectorSale130,352 @ $39.41$5.1M−58.0% of holding−2.0%not yet — horizon still open94,203Form 4 · filed 1 day after the trade
2026-07-01Russell Alan JdirectorSale69,648 @ $39.41$2.7M−73.9% of holding−2.0%not yet — horizon still open24,555Form 4 · filed 1 day after the trade
2026-05-05Donovan Joanne M.officerSale50,000 @ $38.57$1.9M−92.0% of holding−6.7%not yet — horizon still open4,367Form 4 · filed same day
2026-05-04Donovan Joanne M.officerSale5,230 @ $31.29$164K−54.5% of holding+10.1%not yet — horizon still open4,367Form 4 · filed 1 day after the trade
2026-04-01Donovan Joanne M.officerSale28,662 @ $32.31$926K−74.9% of holding−17.6%not yet — horizon still open9,597Form 4 · filed 1 day after the trade
2026-03-31Donovan Joanne M.officerSale21,338 @ $32.12$685K−69.0% of holding−12.2%not yet — horizon still open9,597Form 4 · filed same day
2026-03-27Donovan Joanne M.officerSale9,623 @ $30.98$298K−37.1% of holding−11.8%not yet — horizon still open16,332Form 4 · filed 3 days after the trade
2026-03-27Donovan Joanne M.officerSale6,735 @ $30.98$209K−41.2% of holding−11.8%not yet — horizon still open9,597Form 4 · filed 3 days after the trade
2026-01-21Edris BadreddindirectorSale66,477 @ $29.44$2.0M−77.0% of holding−0.3%+26.1%19,820Form 4 · filed 2 days after the trade
2026-01-21Edris BadreddindirectorSale17,236 @ $29.44$507K−14.2% of holding−0.3%+26.1%104,365Form 4 · filed 2 days after the trade
2026-01-21Edris BadreddindirectorSale13,690 @ $29.44$403K−10.1% of holding−0.3%+26.1%121,601Form 4 · filed 2 days after the trade
2026-01-21Edris BadreddindirectorSale10,463 @ $29.44$308K−10.8% of holding−0.3%+26.1%86,297Form 4 · filed 2 days after the trade
2026-01-21Edris BadreddindirectorSale7,605 @ $29.44$224K−7.3% of holding−0.3%+26.1%96,760Form 4 · filed 2 days after the trade
2025-11-12Russell Alan JdirectorSale100,000 @ $21.12$2.1M−81.0% of holding+11.8%+47.5%23,400Form 4 · filed 1 day after the trade
2025-11-11Fox Jonathan CdirectorPurchase10,700 @ $18.64$199K+82.3% of holding+8.2%+48.2%23,702Form 4 · filed 2 days after the trade
2025-08-26Russell Alan JdirectorSale100,000 @ $14.60$1.5M−81.0% of holding−0.3%+95.7%23,400Form 4 · filed 2 days after the trade
2025-08-12KOCH KEVINdirectorSale7,972 @ $13.39$107K−20.7% of holding+7.2%+120.7%30,615Form 4 · filed 2 days after the trade
2025-08-12Donovan Joanne M.officerSale2,862 @ $13.39$38K−10.1% of holding+7.2%+120.7%25,361Form 4 · filed 2 days after the trade
2025-08-12Derakhshan BehradofficerSale2,491 @ $13.39$33K−9.5% of holding+7.2%+120.7%23,645Form 4 · filed 2 days after the trade
2025-08-12MOORE JOHN RofficerSale2,098 @ $13.39$28K−17.0% of holding+7.2%+120.7%10,214Form 4 · filed 2 days after the trade
2025-08-12Russell Alan JdirectorSale1,907 @ $13.39$26K−7.5% of holding+7.2%+120.7%23,400Form 4 · filed 2 days after the trade
2025-08-12Carruthers R MichaeldirectorSale1,428 @ $13.39$19K−1.6% of holding+7.2%+120.7%86,162Form 4 · filed 2 days after the trade
2025-05-02Donovan Joanne M.officerSale5,187 @ $16.45$85K−19.4% of holding−17.4%−12.9%21,588Form 4 · filed 5 days after the trade
2025-05-02KOCH KEVINdirectorSale4,276 @ $16.45$70K−17.2% of holding−17.4%−12.9%20,619Form 4 · filed 5 days after the trade
2025-05-02MOORE JOHN RofficerSale1,930 @ $16.45$32K−22.8% of holding−17.4%−12.9%6,531Form 4 · filed 5 days after the trade
2025-05-02Derakhshan BehradofficerSale1,691 @ $16.45$28K−7.7% of holding−17.4%−12.9%20,355Form 4 · filed 5 days after the trade
2025-05-02Russell Alan JdirectorSale1,551 @ $16.45$26K−7.7% of holding−17.4%−12.9%18,521Form 4 · filed 5 days after the trade
2025-05-02Carruthers R MichaeldirectorSale1,314 @ $16.45$22K−1.6% of holding−17.4%−12.9%81,014Form 4 · filed 5 days after the trade
2025-04-03Thompson Peter A.directorPurchase372,578 @ $20.13$7.5M+2.6% of holding+16.8%−10.2%14,809,075Form 4 · filed 1 day after the trade
2025-04-03ORBIMED ADVISORS LLCdirectorPurchase372,578 @ $20.13$7.5M+2.6% of holding+16.8%−10.2%14,809,075Form 4 · filed 1 day after the trade
2025-04-03ORBIMED ADVISORS LLCdirectorPurchase124,193 @ $20.13$2.5M+38.9% of holding+16.8%−10.2%443,792Form 4 · filed 1 day after the trade
2025-04-03Thompson Peter A.directorPurchase124,193 @ $20.13$2.5M+38.9% of holding+16.8%−10.2%443,792Form 4 · filed 1 day after the trade
2025-03-07Russell Alan JdirectorSale200 @ $30.02$6K−1.3% of holding−45.6%−60.2%14,863Form 4 · filed 4 days after the trade
2025-03-07KOCH KEVINdirectorSale100 @ $30.00$3K−0.7% of holding−45.6%−60.2%14,478Form 4 · filed 4 days after the trade
2025-02-06Russell Alan JdirectorSale1,200 @ $30.13$36K−7.5% of holding+3.5%−61.5%14,863Form 4 · filed 1 day after the trade
2025-02-06KOCH KEVINdirectorSale900 @ $31.13$28K−5.9% of holding+3.5%−61.5%14,478Form 4 · filed 1 day after the trade
2025-02-05Derakhshan BehradofficerSale10,000 @ $30.03$300K−37.3% of holding−2.0%−62.1%16,837Form 4 · filed 2 days after the trade
2025-02-05KOCH KEVINdirectorSale8,636 @ $30.03$259K−37.4% of holding−2.0%−62.1%14,478Form 4 · filed 2 days after the trade
2025-02-05Russell Alan JdirectorSale8,015 @ $30.02$241K−35.0% of holding−2.0%−62.1%14,863Form 4 · filed 2 days after the trade
2025-01-28Donovan Joanne M.officerSale25,000 @ $27.63$691K−60.4% of holding−1.9%−54.4%16,358Form 4 · filed 2 days after the trade
2024-12-30Russell Alan JdirectorSale100,000 @ $27.37$2.7M−87.1% of holding+1.2%−58.8%14,863Form 4 · filed 1 day after the trade

The vs-S&P columns are a labeled look-back on what the stock did after each filing, measured against the index over the same window. Descriptive history, not a claim about the person or a reason to trade.

185 award / exercise / gift records — not counted as purchases

Awards, option exercises, gifts and tax-withholding disposals are shown separately and never counted as open-market purchases or sales — they carry no conviction information.

DatePersonRoleActionSharesOwned afterFiling
2026-08-12MOORE JOHN RofficerOption exercise6,71822,713Form 4
2026-08-12MOORE JOHN RofficerOption exercise5,78111,563Form 4
2026-08-12MOORE JOHN RofficerOption exercise6,71820,157Form 4
2026-08-12MOORE JOHN RofficerAward / grant32,50032,500Form 4
2026-08-12MOORE JOHN RofficerAward / grant65,00065,000Form 4
2026-08-12Nofi MichaelofficerAward / grant24,37524,375Form 4
2026-08-12Nofi MichaelofficerAward / grant48,75048,750Form 4
2026-08-12Russell Alan JdirectorOption exercise7,03137,367Form 4
2026-08-12Russell Alan JdirectorOption exercise5,78130,336Form 4
2026-08-12Derakhshan BehradofficerAward / grant100,000100,000Form 4
2026-08-12Donovan Joanne M.officerOption exercise5,78111,035Form 4
2026-08-12Donovan Joanne M.officerOption exercise7,03118,066Form 4
2026-08-12Derakhshan BehradofficerOption exercise7,50022,500Form 4
2026-08-12Derakhshan BehradofficerOption exercise5,78111,563Form 4
2026-08-12Donovan Joanne M.officerOption exercise5,78111,563Form 4
2026-08-12Donovan Joanne M.officerOption exercise7,03121,094Form 4
2026-08-12Donovan Joanne M.officerAward / grant32,50032,500Form 4
2026-08-12Donovan Joanne M.officerAward / grant65,00065,000Form 4
2026-08-12KOCH KEVINdirectorOption exercise17,96948,584Form 4
2026-08-12KOCH KEVINdirectorOption exercise21,87570,459Form 4
2026-08-12Derakhshan BehradofficerOption exercise5,78129,426Form 4
2026-08-12Derakhshan BehradofficerOption exercise7,50036,926Form 4
2026-08-12KOCH KEVINdirectorOption exercise17,96935,938Form 4
2026-08-12KOCH KEVINdirectorOption exercise21,87565,625Form 4
2026-08-12KOCH KEVINdirectorAward / grant100,000100,000Form 4
2026-08-12KOCH KEVINdirectorAward / grant200,000200,000Form 4
2026-08-12MOORE JOHN RofficerOption exercise5,78115,995Form 4
2026-08-12Russell Alan JdirectorOption exercise7,03121,094Form 4
2026-08-12Russell Alan JdirectorAward / grant32,50032,500Form 4
2026-08-12Russell Alan JdirectorAward / grant65,00065,000Form 4
2026-08-12Derakhshan BehradofficerAward / grant50,00050,000Form 4
2026-08-12Russell Alan JdirectorOption exercise5,78111,563Form 4
2026-07-01Russell Alan JdirectorOption exercise130,352154,907Form 4
2026-07-01Russell Alan JdirectorOption exercise69,648224,555Form 4
2026-07-01Russell Alan JdirectorOption exercise130,3520Form 4
2026-07-01Russell Alan JdirectorOption exercise69,6481,077,717Form 4
2026-07-01Fox Jonathan CdirectorAward / grant31924,833Form 4
2026-06-05ROOT JONATHAN DdirectorAward / grant16,37716,377Form 4
2026-06-05Brege LauradirectorAward / grant16,37716,377Form 4
2026-06-05Thompson Peter A.directorAward / grant16,37716,377Form 4

Source: SEC Form 4 filings. Each row links to its original filing.

Across 2012–2021, stocks where a CEO, C-suite officer, or director had recently made an open-market common-stock purchase ran about +28 bp per month above the universe average (n=34,268 stock-weeks). A historical tendency, not a prediction.

Congressional disclosures

No congressional trades disclosed for this company.

Research tool, not investment advice — historical frequencies, not recommendations. A product of Marovel Technologies LLC. Full terms.