DNLIDenali Therapeutics Inc.Healthcare · Biotechnologyas of 2026-08-13
Horizon

Issued 2026-08-13 at $25.27 · now $24.82 (2026-08-13, −1.8% since)

Based on its own history, a month from the 2026-08-13 close, DNLI has typically landed between $19.72 and $32.09 — a range of −22.0% to +27.0% from the issuance price $25.27.

Range of outcomes in historically similar periods — not a price prediction. Ranges are scored publicly on /methodology.
  • Actual close
  • Typical path (median)
  • Middle 50% of outcomes
  • 90% range

2,159 overlapping 1 month windows · 2017-12-082026-07-15 · basis climatology · forecast (batch). Probability up 53.8% (90% CI 51.656.0%, ≈1,400 obs).

The cone is anchored at the 2026-08-13 issuance close ($25.27) — the price the forecast resolves against on 2026-09-11, not the latest close. The drawn path shape is illustrative (bands widen with √t); every labeled number is real — the anchor, the scored batch p90/IQR endpoints, and the typical move.

Where DNLI has typically landed a month from the 2026-08-13 close of $25.27 — the range is history, not a prediction.

$19.72worst · -22.0%$32.09best · +27.0%
  • now $24.82 (-1.8%)
  • typicalThe typical outcome — half of similar past periods did better and half did worse (not an average, so a few wild periods don't skew it). $25.03 (-1.0%)
  • middle 50%The central range of outcomes — half of similar past periods landed inside it, a quarter finished above, a quarter below. $22.53$27.52
  • 90% rangeA nine-in-ten range — in about nine of every ten similar past periods the outcome stayed within these bounds. $19.72$32.09
Actual 1-month windows behind the coneiEvery overlapping 1-month window in this security's own price history was ranked by realized return; shown are the 3 worst and 3 best of 2,159 windows spanning 2017-12-08 to 2026-08-13. Not cherry-picked — these are the extremes of the full sample. Max drop / max rise are the deepest and highest points reached within each window. See /methodology.
StartReturnMax dropMax rise
3 worst
2020-02-13−44.4%−44.4%+2.7%
2020-02-11−39.0%−39.0%+6.6%
2020-02-18−37.3%−45.8%+0.0%
3 best
2022-06-16+69.6%+0.0%+69.6%
2022-06-14+61.9%−0.2%+61.9%
2020-10-14+60.7%−8.8%+60.7%

2,159 overlapping windows · 2017-12-082026-08-13 · not cherry-picked

Pending catalysts

  • December 2026Trial primary completion: Phase 1/Phase PHASE2 primary completion: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL593 in Healthy Participants and Participants With Frontotemporal Dementia (FTD-GRN) (source, as of 2026-08-14)
  • March 2027Trial primary completion: Phase 2 primary completion: Safety and Pharmacodynamic Effects of BIIB122 in Participants With LRRK2-Associated Parkinson's Disease (LRRK2-PD) (source, as of 2026-08-14)
  • June 2027Trial primary completion: Phase 2/Phase PHASE3 primary completion: An Extension Study of the Long-Term Safety, Tolerability, and Efficacy of Tividenofusp Alfa (DNL310) in Participants With Mucopolysaccharidosis Type II (MPS II) From Study DNLI-E-0002 or Study DNLI-E-0007 (source, as of 2026-08-14)
  • December 2027Trial primary completion: Phase 2/Phase PHASE3 primary completion: A Study to Determine the Efficacy and Safety of Tividenofusp Alfa (DNL310) vs Idursulfase in Pediatric and Young Adult Participants With Neuronopathic (nMPS II) or Non-Neuronopathic Mucopolysaccharidosis Type II (nnMPS II) (source, as of 2026-08-14)
  • August 2028Trial primary completion: Phase 1/Phase PHASE2 primary completion: Study of DNL126 in Pediatric Participants With Mucopolysaccharidosis Type IIIA (Sanfilippo Syndrome Type A) (source, as of 2026-08-14)
  • February 2031Trial primary completion: Phase 1/Phase PHASE2 primary completion: A Study of Tividenofusp Alfa (DNL310) in Pediatric Participants With Hunter Syndrome (source, as of 2026-08-14)

Public, scheduled events — dated attention, not a prediction of the outcome. See the FDA catalysts page for the historical base rate.

Seasonality · by month iHow this security has tended to do in each calendar month historically — a frequency, never a prediction.

iFor each calendar month, the share of years this security closed higher than the month before, and the average month-over-month return, over ~9 years of its own price history. Cells are shaded by average return. This is historical frequency, not a prediction — no month is a signal.
Jan
56%
+6.9%
n=9
Feb
33%
−2.3%
n=9
Mar
22%
−8.8%
n=9
Apr
56%
+0.8%
n=9
May
78%
+5.6%
n=9
Jun
67%
+7.8%
n=9
Jul
33%
−5.3%
n=9
Aug
67%
+6.9%
n=9
Sep
50%
+2.2%
n=8
Oct
38%
−3.7%
n=8
Nov
63%
+13.7%
n=8
Dec
38%
+1.1%
n=8

Up-frequency and average month-over-month return · historical frequency, not a prediction

Company insiders iOpen-market share purchases and sales by the company's own officers and directors, by filing date.

Last 90 days · as of 2026-08-13 · point-in-time by filing date

No insider transactions on record in the last 90 days.

Congressional disclosures

No congressional trades disclosed for this company.

Research tool, not investment advice — historical frequencies, not recommendations. Full terms.