TNGXTango Therapeutics, Inc.Healthcare · Biotechnologyas of 2026-09-25
Horizon

Issued 2026-09-25 at $24.92 · now $24.92 (2026-09-25, +0.0% since)

Based on its own history, a month from the 2026-09-25 close, TNGX has typically landed between $17.08 and $36.94 — a range of −31.5% to +48.2% from the issuance price $24.92.

Range of outcomes in historically similar periods — not a price prediction. Ranges are scored publicly on /methodology.
  • Actual close
  • Typical path (median)
  • Middle 50% of outcomes
  • 90% range

1,500 overlapping 1 month windows · 2020-09-03 – 2026-08-26 · basis climatology · forecast (batch). Base rate up 53.7% (90% CI 51.5–55.9%, ≈1,391 obs). Not a call on this stock — we have no evidence its odds differ.

The cone is anchored at the 2026-09-25 issuance close ($24.92) — the price the forecast resolves against on 2026-10-26, not the latest close. The drawn path shape is illustrative (bands widen with √t); every labeled number is real — the anchor, the scored batch p90/IQR endpoints, and the typical move.

Where TNGX has typically landed a month from the 2026-09-25 close of $24.92 — the range is history, not a prediction.

$17.08worst · -31.5%$36.94best · +48.2%
  • now $24.92 (+0.0%)
  • typicalThe typical outcome — half of similar past periods did better and half did worse (not an average, so a few wild periods don't skew it). $24.42 (-2.0%)
  • middle 50%The central range of outcomes — half of similar past periods landed inside it, a quarter finished above, a quarter below. $20.54–$28.31
  • 90% rangeA nine-in-ten range — in about nine of every ten similar past periods the outcome stayed within these bounds. $17.08–$36.94
Actual 1-month windows behind the coneiEvery overlapping 1-month window in this security's own price history was ranked by realized return; shown are the 3 worst and 3 best of 1,500 windows spanning 2020-09-03 to 2026-09-25. Not cherry-picked — these are the extremes of the full sample. Max drop / max rise are the deepest and highest points reached within each window. See /methodology.
StartReturnMax dropMax rise
3 worst
2024-10-09−58.3%−58.3%+10.0%
2024-10-10−55.0%−56.8%+13.9%
2024-10-08−53.0%−53.0%+8.3%
3 best
2025-05-09+292.1%+0.0%+292.1%
2025-05-08+278.2%+0.0%+287.3%
2025-05-07+270.4%−4.3%+270.4%

1,500 overlapping windows · 2020-09-03 – 2026-09-25 · not cherry-picked

Pending catalysts

  • 2027-03-31 — Trial primary completion: Phase 1/Phase PHASE2 primary completion: Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss (source, as of 2026-08-14)
  • June 2027 — Trial primary completion: Phase 1/Phase PHASE2 primary completion: Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients (source, as of 2026-08-14)

Public, scheduled events — dated attention, not a prediction of the outcome. See the FDA catalysts page for the historical base rate.

Seasonality · by month iHow this security has tended to do in each calendar month historically — a frequency, never a prediction.

iFor each calendar month, the share of years this security closed higher than the month before, and the average month-over-month return, over ~6 years of its own price history. Cells are shaded by average return. This is historical frequency, not a prediction — no month is a signal.
Jan
33%
+2.4%
n=6
Feb
33%
−8.1%
n=6
Mar
17%
−3.8%
n=6
Apr
50%
−1.4%
n=6
May
33%
+2.5%
n=6
Jun
83%
+31.5%
n=6
Jul
50%
−0.0%
n=6
Aug
83%
+20.6%
n=6
Sep
67%
+12.0%
n=6
Oct
17%
+9.9%
n=6
Nov
33%
−3.1%
n=6
Dec
50%
−0.5%
n=6

Up-frequency and average month-over-month return · historical frequency, not a prediction

Reported insider & political trades

Every Form 4 the people closest to this company have filed with the SEC — plotted against the share price, aggregated by month, and shown with the gap between when each trade happened and when it was disclosed. A public record, not advice.

Share price & reported tradesMonthly open-market valueReporting lag — trade date to filing date2026-092026-082026-072026-062026-052026-042026-032026-022026-012025-122025-112025-102025-092025-08$33$62026-09-22: 3 insider sales, $199K — Newcomb Jessica …2026-09-01: 1 insider sale, $604K — Crystal Adam2026-08-03: 2 insider sales, $736K — Crystal Adam …2026-07-01: 2 insider sales, $799K — Crystal Adam …2026-06-01: 2 insider sales, $618K — Crystal Adam …2026-05-01: 2 insider sales, $573K — Crystal Adam …2026-04-15: 1 insider sale, $962K — Crystal Adam2026-04-01: 1 insider sale, $572K — Crystal Adam2026-03-25: 1 insider sale, $241K — Crystal Adam2026-03-05: 1 insider sale, $304K — Crystal Adam2026-02-25: 1 insider sale, $694K — Crystal Adam2026-02-03: 6 insider sales, $727K — Weber Barbara, Crystal Adam, Beckman Daniella …2025-10-23: 1 insider sale, $4.8M — Third Rock Ventures IV, L.P.2025-09-16: 1 insider sale, $2.6M — Third Rock Ventures IV, L.P.2025-09-08: 1 insider sale, $609K — Third Rock Ventures IV, L.P.2025-09-05: 1 insider sale, $4.5M — Third Rock Ventures IV, L.P.2025-08-22: 1 insider sale, $2.1M — Third Rock Ventures IV, L.P.2025-08: 2 open-market sales, $9.8M2025-09: 3 open-market sales, $7.7M2025-10: 1 open-market sale, $4.8M2026-02: 7 open-market sales, $1.4M2026-03: 2 open-market sales, $545K2026-04: 2 open-market sales, $1.5M2026-05: 2 open-market sales, $573K2026-06: 2 open-market sales, $618K2026-07: 2 open-market sales, $799K2026-08: 2 open-market sales, $736K2026-09: 4 open-market sales, $803K↑ buys↓ salesofficer Newcomb Jessica — Sale on 2026-09-22, filed 2 days after the tradeofficer Newcomb Jessica — Sale on 2026-09-22, filed 2 days after the tradeofficer Newcomb Jessica — Sale on 2026-09-22, filed 2 days after the tradeofficer Crystal Adam — Sale on 2026-09-01, filed 2 days after the tradeofficer Crystal Adam — Sale on 2026-08-03, filed 2 days after the tradeofficer Crystal Adam — Sale on 2026-08-03, filed 2 days after the tradeofficer Crystal Adam — Sale on 2026-07-01, filed 1 day after the tradeofficer Crystal Adam — Sale on 2026-07-01, filed 1 day after the tradeofficer Crystal Adam — Sale on 2026-06-01, filed 2 days after the tradeofficer Crystal Adam — Sale on 2026-06-01, filed 2 days after the tradeofficer Crystal Adam — Sale on 2026-05-01, filed 4 days after the tradeofficer Crystal Adam — Sale on 2026-05-01, filed 4 days after the tradeofficer Crystal Adam — Sale on 2026-04-15, filed 1 day after the tradeofficer Crystal Adam — Sale on 2026-04-01, filed 1 day after the tradeofficer Crystal Adam — Sale on 2026-03-25, filed 2 days after the tradeofficer Crystal Adam — Sale on 2026-03-05, filed 4 days after the tradeofficer Crystal Adam — Sale on 2026-02-25, filed 2 days after the tradedirector Weber Barbara — Sale on 2026-02-03, filed 1 day after the tradeofficer Crystal Adam — Sale on 2026-02-03, filed 1 day after the tradedirector Beckman Daniella — Sale on 2026-02-03, filed 1 day after the tradedirector Weber Barbara — Sale on 2026-02-03, filed 1 day after the tradeofficer Crystal Adam — Sale on 2026-02-03, filed 1 day after the tradedirector Beckman Daniella — Sale on 2026-02-03, filed 1 day after the tradetenPercentOwner Third Rock Ventures IV, L.P. — Sale on 2025-10-23, filed 4 days after the tradetenPercentOwner Third Rock Ventures IV, L.P. — Sale on 2025-09-16, filed 1 day after the tradetenPercentOwner Third Rock Ventures IV, L.P. — Sale on 2025-09-08, filed 1 day after the tradetenPercentOwner Third Rock Ventures IV, L.P. — Sale on 2025-09-05, filed 4 days after the tradetenPercentOwner Third Rock Ventures IV, L.P. — Sale on 2025-08-22, filed 4 days after the trade
DatePersonRoleActionShares @ priceValueOwnership Δvs S&P 1mvs S&P 6mOwned afterFiling
2026-09-22Newcomb JessicaofficerSale5,100 @ $23.97$122K−7.7% of holdingnot yet — horizon still opennot yet — horizon still open61,521Form 4 · filed 2 days after the trade
2026-09-22Newcomb JessicaofficerSale2,400 @ $25.17$60K−3.9% of holdingnot yet — horizon still opennot yet — horizon still open59,121Form 4 · filed 2 days after the trade
2026-09-22Newcomb JessicaofficerSale700 @ $22.80$16K−1.0% of holdingnot yet — horizon still opennot yet — horizon still open66,621Form 4 · filed 2 days after the trade
2026-09-01Crystal AdamofficerSale27,000 @ $22.37$604K−18.9% of holdingnot yet — horizon still opennot yet — horizon still open115,743Form 4 · filed 2 days after the trade
2026-08-03Crystal AdamofficerSale21,733 @ $27.35$594K−15.8% of holding−18.4%not yet — horizon still open115,743Form 4 · filed 2 days after the trade
2026-08-03Crystal AdamofficerSale5,267 @ $26.79$141K−3.7% of holding−18.4%not yet — horizon still open137,476Form 4 · filed 2 days after the trade
2026-07-01Crystal AdamofficerSale19,629 @ $29.34$576K−13.8% of holding−5.6%not yet — horizon still open123,114Form 4 · filed 1 day after the trade
2026-07-01Crystal AdamofficerSale7,371 @ $30.25$223K−6.0% of holding−5.6%not yet — horizon still open115,743Form 4 · filed 1 day after the trade
2026-06-01Crystal AdamofficerSale20,860 @ $23.06$481K−15.3% of holding+25.8%not yet — horizon still open115,743Form 4 · filed 2 days after the trade
2026-06-01Crystal AdamofficerSale6,140 @ $22.25$137K−4.3% of holding+25.8%not yet — horizon still open136,603Form 4 · filed 2 days after the trade
2026-05-01Crystal AdamofficerSale25,900 @ $21.19$549K−18.1% of holding−2.9%not yet — horizon still open116,843Form 4 · filed 4 days after the trade
2026-05-01Crystal AdamofficerSale1,100 @ $22.00$24K−0.9% of holding−2.9%not yet — horizon still open115,743Form 4 · filed 4 days after the trade
2026-04-15Crystal AdamofficerSale38,460 @ $25.00$962K−25.5% of holding−8.7%not yet — horizon still open112,622Form 4 · filed 1 day after the trade
2026-04-01Crystal AdamofficerSale27,000 @ $21.20$572K−19.3% of holding−11.1%not yet — horizon still open112,622Form 4 · filed 1 day after the trade
2026-03-25Crystal AdamofficerSale12,000 @ $20.11$241K−9.6% of holding+14.7%+0.9%112,622Form 4 · filed 2 days after the trade
2026-03-05Crystal AdamofficerSale20,251 @ $15.00$304K−15.2% of holding+23.6%+21.2%112,622Form 4 · filed 4 days after the trade
2026-02-25Crystal AdamofficerSale54,345 @ $12.77$694K−29.0% of holding+63.9%+90.6%132,873Form 4 · filed 2 days after the trade
2026-02-03Weber BarbaradirectorSale30,186 @ $12.26$370K−1.8% of holding+35.3%+117.2%1,629,587Form 4 · filed 1 day after the trade
2026-02-03Crystal AdamofficerSale18,251 @ $12.26$224K−8.9% of holding+35.3%+117.2%187,419Form 4 · filed 1 day after the trade
2026-02-03Beckman DanielladirectorSale10,204 @ $12.26$125K−5.2% of holding+35.3%+117.2%184,410Form 4 · filed 1 day after the trade
2026-02-03Weber BarbaradirectorSale333 @ $12.90$4K−0.0% of holding+35.3%+117.2%1,629,254Form 4 · filed 1 day after the trade
2026-02-03Crystal AdamofficerSale201 @ $12.90$3K−0.1% of holding+35.3%+117.2%187,218Form 4 · filed 1 day after the trade
2026-02-03Beckman DanielladirectorSale113 @ $12.90$1K−0.1% of holding+35.3%+117.2%184,297Form 4 · filed 1 day after the trade
2025-10-23Third Rock Ventures IV, L.P.tenPercentOwnerSale477,401 @ $10.15$4.8M−3.4% of holding+35.1%+242.6%13,386,574Form 4 · filed 4 days after the trade
2025-09-16Third Rock Ventures IV, L.P.tenPercentOwnerSale363,541 @ $7.04$2.6M−2.5% of holding+28.5%+153.4%14,363,975Form 4 · filed 1 day after the trade
2025-09-08Third Rock Ventures IV, L.P.tenPercentOwnerSale86,459 @ $7.04$609K−0.6% of holding+3.6%+137.3%14,727,516Form 4 · filed 1 day after the trade
2025-09-05Third Rock Ventures IV, L.P.tenPercentOwnerSale642,906 @ $7.00$4.5M−4.2% of holding+5.2%+131.6%14,813,975Form 4 · filed 4 days after the trade
2025-08-22Third Rock Ventures IV, L.P.tenPercentOwnerSale302,194 @ $7.00$2.1M−1.9% of holding+2.4%+79.5%15,456,881Form 4 · filed 4 days after the trade
2025-08-19Third Rock Ventures IV, L.P.tenPercentOwnerSale1,100,000 @ $7.01$7.7M−6.5% of holding+9.6%+69.8%15,759,075Form 4 · filed 2 days after the trade
2025-02-05Weber BarbaradirectorSale9,013 @ $3.16$28K−0.6% of holding−35.3%+92.0%1,622,251Form 4 · filed 1 day after the trade
2025-02-05Crystal AdamofficerSale6,851 @ $3.16$22K−4.2% of holding−35.3%+92.0%158,210Form 4 · filed 1 day after the trade
2025-02-05Beckman DanielladirectorSale3,948 @ $3.16$12K−2.6% of holding−35.3%+92.0%150,284Form 4 · filed 1 day after the trade
2025-02-05Barry DouglasofficerSale2,556 @ $3.16$8K−3.7% of holding−35.3%+92.0%66,014Form 4 · filed 1 day after the trade
2025-02-04Weber BarbaradirectorSale9,778 @ $2.99$29K−0.6% of holding−25.8%+108.0%1,631,264Form 4 · filed 2 days after the trade
2025-02-04Crystal AdamofficerSale7,432 @ $2.99$22K−4.3% of holding−25.8%+108.0%165,061Form 4 · filed 2 days after the trade
2025-02-04Beckman DanielladirectorSale4,284 @ $2.99$13K−2.7% of holding−25.8%+108.0%154,232Form 4 · filed 2 days after the trade
2025-02-04Barry DouglasofficerSale2,774 @ $2.99$8K−3.9% of holding−25.8%+108.0%68,570Form 4 · filed 2 days after the trade
2024-11-18Rothenberg MacedirectorPurchase10,000 @ $3.78$38K+47.1% of holding−22.2%−47.8%31,250Form 4 · filed same day
2024-11-14Rothenberg MacedirectorPurchase10,000 @ $3.62$36K+88.9% of holding−27.0%−47.7%21,250Form 4 · filed 4 days after the trade
2024-11-07EcoR1 Capital, LLCdirectorSale1,143,124 @ $2.92$3.3M−9.7% of holding+11.9%−49.7%10,630,736Form 4 · filed 1 day after the trade
2024-11-07EcoR1 Capital, LLCdirectorSale62,318 @ $3.29$205K−0.5% of holding+11.9%−49.7%11,773,860Form 4 · filed 1 day after the trade
2024-11-06Boxer Capital Management, LLCotherSale3,080,000 @ $3.14$9.7M−46.0% of holding+1.8%−58.8%3,610,642Form 4 · filed 1 day after the trade
2024-11-06EcoR1 Capital, LLCdirectorSale1,494,558 @ $3.28$4.9M−11.2% of holding+1.8%−58.8%11,836,178Form 4 · filed 2 days after the trade
2024-10-25Boxer Capital Management, LLCotherSale633,000 @ $6.87$4.3M−8.6% of holding−39.1%−72.6%6,690,642Form 4 · filed 3 days after the trade
2024-10-22Boxer Capital Management, LLCotherSale250,000 @ $6.78$1.7M−3.3% of holding−39.8%−73.0%7,323,642Form 4 · filed 1 day after the trade
2024-10-21Boxer Capital Management, LLCotherSale625,000 @ $7.05$4.4M−7.6% of holding−47.3%−73.8%7,573,642Form 4 · filed 2 days after the trade
2024-09-13Third Rock Ventures IV, L.P.tenPercentOwnerSale67,400 @ $10.53$710K−0.4% of holding−39.1%−83.6%16,859,075Form 4 · filed 4 days after the trade
2024-09-05Third Rock Ventures IV, L.P.tenPercentOwnerSale75,000 @ $11.56$867K−0.4% of holding−44.8%−86.7%16,926,475Form 4 · filed 4 days after the trade
2024-08-30Third Rock Ventures IV, L.P.tenPercentOwnerSale175,000 @ $11.60$2.0M−1.0% of holding−39.6%−86.4%17,001,475Form 4 · filed 5 days after the trade
2024-08-27Third Rock Ventures IV, L.P.tenPercentOwnerSale25,000 @ $11.55$289K−0.1% of holding−37.7%−88.3%17,176,475Form 4 · filed 2 days after the trade
2024-08-19Third Rock Ventures IV, L.P.tenPercentOwnerSale150,000 @ $10.09$1.5M−0.9% of holding−22.8%−87.0%17,201,475Form 4 · filed 1 day after the trade
2024-08-16Third Rock Ventures IV, L.P.tenPercentOwnerSale135,000 @ $9.79$1.3M−0.8% of holding−15.0%−87.1%17,351,475Form 4 · filed 4 days after the trade
2024-08-01Third Rock Ventures IV, L.P.tenPercentOwnerSale40,000 @ $9.80$392K−0.2% of holding+21.4%−80.0%17,486,475Form 4 · filed same day
2024-07-31Third Rock Ventures IV, L.P.tenPercentOwnerSale100,000 @ $9.93$993K−0.6% of holding+11.5%−79.7%17,526,475Form 4 · filed 1 day after the trade
2024-07-30Third Rock Ventures IV, L.P.tenPercentOwnerSale95,000 @ $9.80$931K−0.5% of holding+13.9%−80.3%17,626,475Form 4 · filed 2 days after the trade
2024-07-26Third Rock Ventures IV, L.P.tenPercentOwnerSale50,000 @ $9.84$492K−0.3% of holding+19.4%−79.8%17,721,475Form 4 · filed 4 days after the trade
2024-07-25Third Rock Ventures IV, L.P.tenPercentOwnerSale100,599 @ $9.87$993K−0.6% of holding+13.1%−81.0%17,771,475Form 4 · filed 1 day after the trade
2024-07-24Third Rock Ventures IV, L.P.tenPercentOwnerSale200,000 @ $9.82$2.0M−1.1% of holding+8.4%−82.4%17,872,074Form 4 · filed 2 days after the trade
2024-07-23Third Rock Ventures IV, L.P.tenPercentOwnerSale125,000 @ $9.79$1.2M−0.7% of holding+5.4%−79.5%18,072,074Form 4 · filed 1 day after the trade
2024-07-22Third Rock Ventures IV, L.P.tenPercentOwnerSale262,740 @ $9.78$2.6M−1.4% of holding+11.6%−78.9%18,197,074Form 4 · filed 2 days after the trade

The vs-S&P columns are a labeled look-back on what the stock did after each filing, measured against the index over the same window. Descriptive history, not a claim about the person or a reason to trade.

70 award / exercise / gift records — not counted as purchases

Awards, option exercises, gifts and tax-withholding disposals are shown separately and never counted as open-market purchases or sales — they carry no conviction information.

DatePersonRoleActionSharesOwned afterFiling
2026-09-01Crystal AdamofficerOption exercise27,000142,743Form 4
2026-09-01Crystal AdamofficerOption exercise27,000260,040Form 4
2026-08-03Crystal AdamofficerOption exercise27,000142,743Form 4
2026-08-03Crystal AdamofficerOption exercise27,000287,040Form 4
2026-07-01Crystal AdamofficerOption exercise27,000142,743Form 4
2026-07-01Crystal AdamofficerOption exercise27,000314,040Form 4
2026-06-19Azelby RobertdirectorAward / grant5,7405,740Form 4
2026-06-19Azelby RobertdirectorAward / grant35,91035,910Form 4
2026-06-05Lee SungdirectorAward / grant3,5703,570Form 4
2026-06-05Rothenberg MacedirectorAward / grant4,00041,500Form 4
2026-06-05Rothenberg MacedirectorAward / grant25,00025,000Form 4
2026-06-05Ketchum John BdirectorAward / grant25,00025,000Form 4
2026-06-05Lee SungdirectorAward / grant57022,870Form 4
2026-06-05Ketchum John BdirectorAward / grant4,00024,937Form 4
2026-06-05Calhoun Lesley AnndirectorAward / grant25,00025,000Form 4
2026-06-05Calhoun Lesley AnndirectorAward / grant4,00016,500Form 4
2026-06-01Crystal AdamofficerOption exercise27,000142,743Form 4
2026-06-01Crystal AdamofficerOption exercise27,000341,040Form 4
2026-05-01Crystal AdamofficerOption exercise27,000142,743Form 4
2026-05-01Gall MatthewofficerAward / grant240,000240,000Form 4
2026-05-01Crystal AdamofficerOption exercise27,000368,040Form 4
2026-05-01Gall MatthewofficerAward / grant40,00040,000Form 4
2026-04-29Lee SungdirectorAward / grant12,30022,300Form 4
2026-04-29Lee SungdirectorAward / grant5,2005,200Form 4
2026-04-15Crystal AdamofficerOption exercise38,460151,082Form 4
2026-04-15Crystal AdamofficerOption exercise38,460395,040Form 4
2026-04-01Crystal AdamofficerOption exercise27,000139,622Form 4
2026-04-01Crystal AdamofficerOption exercise27,000433,500Form 4
2026-03-25Crystal AdamofficerOption exercise12,000124,622Form 4
2026-03-25Crystal AdamofficerOption exercise12,000460,500Form 4
2026-02-02Beckman DanielladirectorAward / grant265,980265,980Form 4
2026-02-02Crystal AdamofficerAward / grant47,460205,670Form 4
2026-02-02Weber BarbaradirectorAward / grant37,5221,659,773Form 4
2026-02-02Crystal AdamofficerAward / grant284,760284,760Form 4
2026-02-02Beckman DanielladirectorAward / grant44,330194,614Form 4
2026-02-02Weber BarbaradirectorAward / grant222,132222,132Form 4
2026-01-08Peters MaltedirectorAward / grant1,650,0001,650,000Form 4
2026-01-08Peters MaltedirectorAward / grant350,000367,500Form 4
2026-01-02Lee SungdirectorAward / grant60,00060,000Form 4
2026-01-02Lee SungdirectorAward / grant10,00010,000Form 4

Source: SEC Form 4 filings. Each row links to its original filing.

Across 2012–2021, stocks where a CEO, C-suite officer, or director had recently made an open-market common-stock purchase ran about +28 bp per month above the universe average (n=34,268 stock-weeks). A historical tendency, not a prediction.

Congressional disclosures

No congressional trades disclosed for this company.

Research tool, not investment advice — historical frequencies, not recommendations. A product of Marovel Technologies LLC. Full terms.