SYRESpyre Therapeutics, Inc.Healthcare · Biotechnologyas of 2026-08-13
Horizon

Issued 2026-08-13 at $104.09 · now $101.85 (2026-08-13, −2.2% since)

Based on its own history, a month from the 2026-08-13 close, SYRE has typically landed between $65.52 and $164.16 — a range of −37.1% to +57.7% from the issuance price $104.09.

Range of outcomes in historically similar periods — not a price prediction. Ranges are scored publicly on /methodology.
  • Actual close
  • Typical path (median)
  • Middle 50% of outcomes
  • 90% range

2,578 overlapping 1 month windows · 2016-04-072026-07-15 · basis climatology · forecast (batch). Probability up 53.8% (90% CI 51.656.0%, ≈1,400 obs).

The cone is anchored at the 2026-08-13 issuance close ($104.09) — the price the forecast resolves against on 2026-09-11, not the latest close. The drawn path shape is illustrative (bands widen with √t); every labeled number is real — the anchor, the scored batch p90/IQR endpoints, and the typical move.

Where SYRE has typically landed a month from the 2026-08-13 close of $104.09 — the range is history, not a prediction.

$65.52worst · -37.1%$164.16best · +57.7%
  • now $101.85 (-2.2%)
  • typicalThe typical outcome — half of similar past periods did better and half did worse (not an average, so a few wild periods don't skew it). $103.58 (-0.5%)
  • middle 50%The central range of outcomes — half of similar past periods landed inside it, a quarter finished above, a quarter below. $85.93$121.22
  • 90% rangeA nine-in-ten range — in about nine of every ten similar past periods the outcome stayed within these bounds. $65.52$164.16
Actual 1-month windows behind the coneiEvery overlapping 1-month window in this security's own price history was ranked by realized return; shown are the 3 worst and 3 best of 2,578 windows spanning 2016-04-07 to 2026-08-13. Not cherry-picked — these are the extremes of the full sample. Max drop / max rise are the deepest and highest points reached within each window. See /methodology.
StartReturnMax dropMax rise
3 worst
2022-11-10−74.7%−75.6%+0.0%
2022-11-11−71.9%−72.6%+0.0%
2022-11-16−71.9%−71.9%+0.0%
3 best
2023-06-21+456.6%+0.0%+538.5%
2023-06-14+366.1%−27.0%+366.1%
2023-06-15+334.8%−28.0%+359.8%

2,578 overlapping windows · 2016-04-072026-08-13 · not cherry-picked

Pending catalysts

  • 2026-10-31Trial primary completion: Phase 2 primary completion: A Study of SPY072 in Rheumatic Disease (source, as of 2026-08-14)
  • June 2027Trial primary completion: Phase 2 primary completion: A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis (source, as of 2026-08-14)
  • 2029-03-02Trial primary completion: Phase 2 primary completion: Long-term Safety and Efficacy of Multiple Long-acting Antibodies Alone and in Combinations for IBD (source, as of 2026-08-14)

Public, scheduled events — dated attention, not a prediction of the outcome. See the FDA catalysts page for the historical base rate.

Seasonality · by month iHow this security has tended to do in each calendar month historically — a frequency, never a prediction.

iFor each calendar month, the share of years this security closed higher than the month before, and the average month-over-month return, over ~11 years of its own price history. Cells are shaded by average return. This is historical frequency, not a prediction — no month is a signal.
Jan
40%
+3.5%
n=10
Feb
50%
+2.9%
n=10
Mar
50%
+2.2%
n=10
Apr
20%
−1.0%
n=10
May
45%
−5.5%
n=11
Jun
45%
+12.7%
n=11
Jul
45%
+0.8%
n=11
Aug
82%
+10.2%
n=11
Sep
60%
+1.6%
n=10
Oct
40%
+10.9%
n=10
Nov
50%
+8.3%
n=10
Dec
30%
−9.1%
n=10

Up-frequency and average month-over-month return · historical frequency, not a prediction

Company insiders iOpen-market share purchases and sales by the company's own officers and directors, by filing date.

Last 90 days · as of 2026-08-13 · point-in-time by filing date

No insider transactions on record in the last 90 days.

Congressional disclosures

No congressional trades disclosed for this company.

Research tool, not investment advice — historical frequencies, not recommendations. Full terms.