SEPNSepterna IncHealthcare · Biotechnologyas of 2026-09-16
Horizon

Issued 2026-09-16 at $38.44 · now $38.44 (2026-09-16, +0.0% since)

Based on its own history, a month from the 2026-09-16 close, SEPN has typically landed between $29.00 and $55.95 — a range of −24.6% to +45.6% from the issuance price $38.44.

Range of outcomes in historically similar periods — not a price prediction. Ranges are scored publicly on /methodology.
  • Actual close
  • Typical path (median)
  • Middle 50% of outcomes
  • 90% range

452 overlapping 1 month windows · 2024-10-252026-08-17 · basis climatology · forecast (batch). Probability up 53.9% (90% CI 51.756.1%, ≈1,408 obs).

The cone is anchored at the 2026-09-16 issuance close ($38.44) — the price the forecast resolves against on 2026-10-15, not the latest close. The drawn path shape is illustrative (bands widen with √t); every labeled number is real — the anchor, the scored batch p90/IQR endpoints, and the typical move.

Where SEPN has typically landed a month from the 2026-09-16 close of $38.44 — the range is history, not a prediction.

$29worst · -24.6%$55.95best · +45.6%
  • now $38.44 (+0.0%)
  • typicalThe typical outcome — half of similar past periods did better and half did worse (not an average, so a few wild periods don't skew it). $40.7 (+5.9%)
  • middle 50%The central range of outcomes — half of similar past periods landed inside it, a quarter finished above, a quarter below. $34.64$46.77
  • 90% rangeA nine-in-ten range — in about nine of every ten similar past periods the outcome stayed within these bounds. $29$55.95
Actual 1-month windows behind the coneiEvery overlapping 1-month window in this security's own price history was ranked by realized return; shown are the 3 worst and 3 best of 452 windows spanning 2024-10-25 to 2026-09-16. Not cherry-picked — these are the extremes of the full sample. Max drop / max rise are the deepest and highest points reached within each window. See /methodology.
StartReturnMax dropMax rise
3 worst
2025-01-24−70.1%−70.1%+0.0%
2025-01-22−70.1%−71.4%+0.0%
2025-01-23−68.8%−69.8%+0.5%
3 best
2025-04-17+69.0%−0.5%+72.2%
2025-09-12+68.7%+0.0%+68.7%
2025-04-14+67.4%−3.3%+67.4%

452 overlapping windows · 2024-10-252026-09-16 · not cherry-picked

Seasonality · by month iHow this security has tended to do in each calendar month historically — a frequency, never a prediction.

iFor each calendar month, the share of years this security closed higher than the month before, and the average month-over-month return, over ~2 years of its own price history. Cells are shaded by average return. This is historical frequency, not a prediction — no month is a signal.
Jan
0%
−21.2%
n=2
Feb
50%
−18.7%
n=2
Mar
0%
−13.9%
n=2
Apr
50%
+9.5%
n=2
May
100%
+30.0%
n=2
Jun
100%
+12.6%
n=2
Jul
100%
+10.1%
n=2
Aug
50%
+4.1%
n=2
Sep
100%
+28.1%
n=2
Oct
100%
+9.5%
n=1
Nov
100%
+25.7%
n=2
Dec
0%
−6.7%
n=2

Up-frequency and average month-over-month return · historical frequency, not a prediction

Reported insider & political trades

Every Form 4 the people closest to this company have filed with the SEC — plotted against the share price, aggregated by month, and shown with the gap between when each trade happened and when it was disclosed. A public record, not advice.

Share price & reported tradesMonthly open-market valueReporting lag — trade date to filing date2026-092026-082026-072026-062026-052026-042026-032026-022026-012025-122025-112025-102025-092025-08$48$112026-09-01: 1 insider sale, $126K — Long Daniel D.2026-08-12: 4 insider sales, $70.9M — RA CAPITAL MANAGEMENT, L.P., Third Rock Ventures V, L.P. …2026-08-11: 1 insider sale, $1.1M — Bhatt Elizabeth2026-08-03: 2 insider sales, $115K — Long Daniel D. …2026-07-15: 1 insider sale, $136K — Bhatt Elizabeth2026-07-01: 2 insider sales, $115K — Long Daniel D. …2026-06-29: 1 insider sale, $77K — Shaikhly Samira2026-06-22: 2 insider sales, $533K — Long Daniel D. …2026-06-12: 1 insider sale, $219K — Shaikhly Samira2026-06-01: 3 insider sales, $172K — Shaikhly Samira …2026-05-26: 1 insider sale, $355K — Shaikhly Samira2026-04-15: 3 insider sales, $97K — Bhatt Elizabeth …2026-03-02: 2 insider sales, $2.0M — Shaikhly Samira …2026-02-18: 2 insider sales, $116K — Bhatt Elizabeth …2025-11-10: 1 insider sale, $63K — Long Daniel D.2025-11: 1 open-market sale, $63K2026-02: 2 open-market sales, $116K2026-03: 2 open-market sales, $2.0M2026-04: 3 open-market sales, $97K2026-05: 1 open-market sale, $355K2026-06: 7 open-market sales, $1.0M2026-07: 3 open-market sales, $251K2026-08: 7 open-market sales, $72.1M2026-09: 1 open-market sale, $126K↑ buys↓ salesofficer Long Daniel D. — Sale on 2026-09-01, filed 2 days after the tradedirector RA CAPITAL MANAGEMENT, L.P. — Sale on 2026-08-12, filed 2 days after the tradedirector RA CAPITAL MANAGEMENT, L.P. — Sale on 2026-08-12, filed 2 days after the tradetenPercentOwner Third Rock Ventures V, L.P. — Sale on 2026-08-12, filed 2 days after the tradetenPercentOwner Third Rock Ventures V, L.P. — Sale on 2026-08-12, filed 2 days after the tradeofficer Bhatt Elizabeth — Sale on 2026-08-11, filed 2 days after the tradeofficer Long Daniel D. — Sale on 2026-08-03, filed 2 days after the tradeofficer Long Daniel D. — Sale on 2026-08-03, filed 2 days after the tradeofficer Bhatt Elizabeth — Sale on 2026-07-15, filed 2 days after the tradeofficer Long Daniel D. — Sale on 2026-07-01, filed 1 day after the tradeofficer Long Daniel D. — Sale on 2026-07-01, filed 1 day after the tradeofficer Shaikhly Samira — Sale on 2026-06-29, filed 1 day after the tradeofficer Long Daniel D. — Sale on 2026-06-22, filed 2 days after the tradeofficer Long Daniel D. — Sale on 2026-06-22, filed 2 days after the tradeofficer Shaikhly Samira — Sale on 2026-06-12, filed 4 days after the tradeofficer Shaikhly Samira — Sale on 2026-06-01, filed 2 days after the tradeofficer Shaikhly Samira — Sale on 2026-06-01, filed 2 days after the tradeofficer Shaikhly Samira — Sale on 2026-06-01, filed 2 days after the tradeofficer Shaikhly Samira — Sale on 2026-05-26, filed 2 days after the tradeofficer Bhatt Elizabeth — Sale on 2026-04-15, filed 2 days after the tradeofficer Bhatt Elizabeth — Sale on 2026-04-15, filed 2 days after the tradeofficer Bhatt Elizabeth — Sale on 2026-04-15, filed 2 days after the tradeofficer Shaikhly Samira — Sale on 2026-03-02, filed 2 days after the tradeofficer Shaikhly Samira — Sale on 2026-03-02, filed 2 days after the tradeofficer Bhatt Elizabeth — Sale on 2026-02-18, filed 2 days after the tradeofficer Bhatt Elizabeth — Sale on 2026-02-18, filed 2 days after the tradeofficer Long Daniel D. — Sale on 2025-11-10, filed 3 days after the trade
DatePersonRoleActionShares @ priceValueOwnership Δvs S&P 1mvs S&P 6mOwned afterFiling
2026-09-01Long Daniel D.officerSale3,333 @ $37.83$126K−3.3% of holdingnot yet — horizon still opennot yet — horizon still open96,412Form 4 · filed 2 days after the trade
2026-08-12RA CAPITAL MANAGEMENT, L.P.directorSale746,500 @ $42.50$31.7M−50.7% of holding−19.0%not yet — horizon still open725,443Form 4 · filed 2 days after the trade
2026-08-12RA CAPITAL MANAGEMENT, L.P.directorSale746,500 @ $42.50$31.7M−13.5% of holding−19.0%not yet — horizon still open4,777,415Form 4 · filed 2 days after the trade
2026-08-12Third Rock Ventures V, L.P.tenPercentOwnerSale147,059 @ $50.27$7.4M+2.5% of holding−19.0%not yet — horizon still open6,068,532Form 4 · filed 2 days after the trade
2026-08-12Third Rock Ventures V, L.P.tenPercentOwnerSale141 @ $51.08$7K+0.0% of holding−19.0%not yet — horizon still open6,068,391Form 4 · filed 2 days after the trade
2026-08-11Bhatt ElizabethofficerSale25,000 @ $44.00$1.1M−12.5% of holding−19.3%not yet — horizon still open174,209Form 4 · filed 2 days after the trade
2026-08-03Long Daniel D.officerSale2,334 @ $34.68$81K−2.4% of holding+7.2%not yet — horizon still open96,412Form 4 · filed 2 days after the trade
2026-08-03Long Daniel D.officerSale1,000 @ $33.98$34K−1.0% of holding+7.2%not yet — horizon still open98,746Form 4 · filed 2 days after the trade
2026-07-15Bhatt ElizabethofficerSale4,000 @ $33.99$136K−2.2% of holding+29.4%not yet — horizon still open174,209Form 4 · filed 2 days after the trade
2026-07-01Long Daniel D.officerSale2,100 @ $34.10$72K−2.1% of holding−0.6%not yet — horizon still open97,645Form 4 · filed 1 day after the trade
2026-07-01Long Daniel D.officerSale1,233 @ $34.81$43K−1.3% of holding−0.6%not yet — horizon still open96,412Form 4 · filed 1 day after the trade
2026-06-29Shaikhly SamiraofficerSale2,178 @ $35.18$77K−73.3% of holding−1.7%not yet — horizon still open793Form 4 · filed 1 day after the trade
2026-06-22Long Daniel D.officerSale8,000 @ $35.10$281K−7.2% of holding−2.3%not yet — horizon still open103,412Form 4 · filed 2 days after the trade
2026-06-22Long Daniel D.officerSale7,000 @ $35.97$252K−6.8% of holding−2.3%not yet — horizon still open96,412Form 4 · filed 2 days after the trade
2026-06-12Shaikhly SamiraofficerSale6,250 @ $35.08$219K−88.7% of holding−7.3%not yet — horizon still open793Form 4 · filed 4 days after the trade
2026-06-01Shaikhly SamiraofficerSale2,889 @ $29.66$86K−78.5% of holding+16.9%not yet — horizon still open793Form 4 · filed 2 days after the trade
2026-06-01Shaikhly SamiraofficerSale1,700 @ $27.78$47K−25.3% of holding+16.9%not yet — horizon still open5,028Form 4 · filed 2 days after the trade
2026-06-01Shaikhly SamiraofficerSale1,346 @ $28.79$39K−26.8% of holding+16.9%not yet — horizon still open3,682Form 4 · filed 2 days after the trade
2026-05-26Shaikhly SamiraofficerSale11,798 @ $30.06$355K−93.7% of holding+14.6%not yet — horizon still open793Form 4 · filed 2 days after the trade
2026-04-15Bhatt ElizabethofficerSale2,573 @ $23.76$61K−1.4% of holding+2.3%not yet — horizon still open175,636Form 4 · filed 2 days after the trade
2026-04-15Bhatt ElizabethofficerSale1,101 @ $25.24$28K−0.6% of holding+2.3%not yet — horizon still open174,535Form 4 · filed 2 days after the trade
2026-04-15Bhatt ElizabethofficerSale326 @ $25.86$8K−0.2% of holding+2.3%not yet — horizon still open174,209Form 4 · filed 2 days after the trade
2026-03-02Shaikhly SamiraofficerSale66,363 @ $28.14$1.9M−98.8% of holding−11.1%+20.9%793Form 4 · filed 2 days after the trade
2026-03-02Shaikhly SamiraofficerSale4,090 @ $27.51$112K−5.7% of holding−11.1%+20.9%67,156Form 4 · filed 2 days after the trade
2026-02-18Bhatt ElizabethofficerSale2,200 @ $28.46$63K−1.2% of holding−10.3%+42.6%176,009Form 4 · filed 2 days after the trade
2026-02-18Bhatt ElizabethofficerSale1,800 @ $29.58$53K−1.0% of holding−10.3%+42.6%174,209Form 4 · filed 2 days after the trade
2025-11-10Long Daniel D.officerSale3,501 @ $18.06$63K−3.6% of holding+40.8%+27.2%92,911Form 4 · filed 3 days after the trade
2025-03-07Ezekowitz AlandirectorPurchase13,319 @ $6.93$92K+12.8% of holding−4.2%+114.8%117,420Form 4 · filed 3 days after the trade
2025-03-06Ezekowitz AlandirectorPurchase41,355 @ $6.00$248K+65.9% of holding−2.3%+113.2%104,101Form 4 · filed same day
2025-03-05Ezekowitz AlandirectorPurchase37,835 @ $5.82$220K+151.9% of holding+5.5%+126.1%62,746Form 4 · filed 1 day after the trade
2025-03-04Ezekowitz AlandirectorPurchase7,491 @ $6.35$48K+43.0% of holding−9.0%+116.3%24,911Form 4 · filed 2 days after the trade
2025-02-27Labrucherie Gil MdirectorPurchase3,718 @ $5.85$22K+10.2% of holding+9.9%+100.1%40,000Form 4 · filed same day
2025-02-27Finer JeffreydirectorPurchase3,000 @ $5.80$17K+0.4% of holding+9.9%+100.1%771,907Form 4 · filed same day
2025-02-26Finer JeffreydirectorPurchase4,000 @ $5.70$23K+0.5% of holding+14.7%+112.2%768,907Form 4 · filed 1 day after the trade
2025-02-25Finer JeffreydirectorPurchase10,000 @ $5.68$57K+1.3% of holding+15.3%+120.9%764,907Form 4 · filed 2 days after the trade
2025-02-25Labrucherie Gil MdirectorPurchase6,282 @ $5.59$35K+20.9% of holding+15.3%+120.9%36,282Form 4 · filed 2 days after the trade
2025-02-24Third Rock Ventures VI, L.P.tenPercentOwnerPurchase18,861 @ $6.00$113K+0.4% of holding+9.8%+100.5%4,211,659Form 4 · filed 2 days after the trade
2025-02-21Third Rock Ventures VI, L.P.tenPercentOwnerPurchase427,668 @ $5.94$2.5M+11.4% of holding+13.9%+98.5%4,192,798Form 4 · filed 3 days after the trade
2025-02-21Labrucherie Gil MdirectorPurchase5,000 @ $5.85$29K+20.0% of holding+13.9%+98.5%30,000Form 4 · filed same day
2025-02-20Third Rock Ventures VI, L.P.tenPercentOwnerPurchase612,674 @ $5.92$3.6M+19.4% of holding+7.8%+93.9%3,765,130Form 4 · filed 4 days after the trade
2025-02-20Labrucherie Gil MdirectorPurchase14,500 @ $5.88$85K+138.1% of holding+7.8%+93.9%25,000Form 4 · filed 1 day after the trade
2025-02-19Labrucherie Gil MdirectorPurchase10,500 @ $5.51$58Kownership Δ n/a+18.6%+95.1%10,500Form 4 · filed 2 days after the trade

The vs-S&P columns are a labeled look-back on what the stock did after each filing, measured against the index over the same window. Descriptive history, not a claim about the person or a reason to trade.

83 award / exercise / gift records — not counted as purchases

Awards, option exercises, gifts and tax-withholding disposals are shown separately and never counted as open-market purchases or sales — they carry no conviction information.

DatePersonRoleActionSharesOwned afterFiling
2026-09-08Patni RajivdirectorAward / grant275,000275,000Form 4
2026-09-01Long Daniel D.officerOption exercise3,33399,745Form 4
2026-09-01Long Daniel D.officerOption exercise3,3339,085Form 4
2026-08-11Bhatt ElizabethofficerOption exercise18,681192,890Form 4
2026-08-11Bhatt ElizabethofficerOption exercise6,319199,209Form 4
2026-08-11Bhatt ElizabethofficerOption exercise18,68162,230Form 4
2026-08-11Bhatt ElizabethofficerOption exercise6,31982,332Form 4
2026-08-03Long Daniel D.officerOption exercise1,81698,228Form 4
2026-08-03Long Daniel D.officerOption exercise1,51899,746Form 4
2026-08-03Long Daniel D.officerOption exercise1,51812,418Form 4
2026-08-03Long Daniel D.officerOption exercise1,8165,227Form 4
2026-07-15Bhatt ElizabethofficerOption exercise4,000178,209Form 4
2026-07-15Bhatt ElizabethofficerOption exercise4,00080,911Form 4
2026-07-01Long Daniel D.officerOption exercise3,33399,745Form 4
2026-07-01Long Daniel D.officerOption exercise3,3337,043Form 4
2026-06-29Shaikhly SamiraofficerOption exercise2,1782,971Form 4
2026-06-29Shaikhly SamiraofficerOption exercise2,17820,865Form 4
2026-06-26Coulie BernarddirectorAward / grant15,00015,000Form 4
2026-06-26Ezekowitz AlandirectorAward / grant15,00015,000Form 4
2026-06-26Gottesdiener Keith MichaeldirectorAward / grant11,26011,260Form 4
2026-06-26RA CAPITAL MANAGEMENT, L.P.directorAward / grant15,00015,000Form 4
2026-06-26Simson JakedirectorAward / grant15,00015,000Form 4
2026-06-26Tong Jeffrey KdirectorAward / grant15,00015,000Form 4
2026-06-26Sharp ShalinidirectorAward / grant15,00015,000Form 4
2026-06-26Bassan AbrahamdirectorAward / grant15,00015,000Form 4
2026-06-22Long Daniel D.officerOption exercise4,471111,412Form 4
2026-06-22Long Daniel D.officerOption exercise10,529106,941Form 4
2026-06-22Long Daniel D.officerOption exercise10,52910,376Form 4
2026-06-22Long Daniel D.officerOption exercise4,47125,529Form 4
2026-06-12Shaikhly SamiraofficerOption exercise6,2507,043Form 4
2026-06-12Shaikhly SamiraofficerOption exercise6,25023,750Form 4
2026-06-01Shaikhly SamiraofficerOption exercise4,3555,148Form 4
2026-06-01Shaikhly SamiraofficerOption exercise9436,091Form 4
2026-06-01Shaikhly SamiraofficerOption exercise6376,728Form 4
2026-06-01Shaikhly SamiraofficerOption exercise6374,464Form 4
2026-06-01Shaikhly SamiraofficerOption exercise4,35511,614Form 4
2026-06-01Shaikhly SamiraofficerOption exercise9432,517Form 4
2026-05-26Shaikhly SamiraofficerOption exercise11,79812,591Form 4
2026-05-26Shaikhly SamiraofficerOption exercise11,79823,043Form 4
2026-04-15Bhatt ElizabethofficerOption exercise4,000178,209Form 4

Source: SEC Form 4 filings. Each row links to its original filing.

Across 2012–2021, stocks where a CEO, C-suite officer, or director had recently made an open-market common-stock purchase ran about +28 bp per month above the universe average (n=34,268 stock-weeks). A historical tendency, not a prediction.

Congressional disclosures

No congressional trades disclosed for this company.

Research tool, not investment advice — historical frequencies, not recommendations. A product of Marovel Technologies LLC. Full terms.