PTGXProtagonist Therapeutics, Inc.Healthcare · Biotechnologyas of 2026-09-16
Horizon

Issued 2026-09-16 at $142.84 · now $142.84 (2026-09-16, +0.0% since)

Based on its own history, a month from the 2026-09-16 close, PTGX has typically landed between $114.42 and $190.83 — a range of −19.9% to +33.6% from the issuance price $142.84.

Range of outcomes in historically similar periods — not a price prediction. Ranges are scored publicly on /methodology.
  • Actual close
  • Typical path (median)
  • Middle 50% of outcomes
  • 90% range

2,513 overlapping 1 month windows · 2016-08-112026-08-17 · basis climatology · forecast (batch). Probability up 53.9% (90% CI 51.756.1%, ≈1,408 obs).

The cone is anchored at the 2026-09-16 issuance close ($142.84) — the price the forecast resolves against on 2026-10-15, not the latest close. The drawn path shape is illustrative (bands widen with √t); every labeled number is real — the anchor, the scored batch p90/IQR endpoints, and the typical move.

Where PTGX has typically landed a month from the 2026-09-16 close of $142.84 — the range is history, not a prediction.

$114.42worst · -19.9%$190.83best · +33.6%
  • now $142.84 (+0.0%)
  • typicalThe typical outcome — half of similar past periods did better and half did worse (not an average, so a few wild periods don't skew it). $149.07 (+4.4%)
  • middle 50%The central range of outcomes — half of similar past periods landed inside it, a quarter finished above, a quarter below. $133.5$164.64
  • 90% rangeA nine-in-ten range — in about nine of every ten similar past periods the outcome stayed within these bounds. $114.42$190.83
Actual 1-month windows behind the coneiEvery overlapping 1-month window in this security's own price history was ranked by realized return; shown are the 3 worst and 3 best of 2,513 windows spanning 2016-08-11 to 2026-09-16. Not cherry-picked — these are the extremes of the full sample. Max drop / max rise are the deepest and highest points reached within each window. See /methodology.
StartReturnMax dropMax rise
3 worst
2021-08-18−72.2%−72.2%+6.5%
2021-08-20−68.6%−73.7%+1.0%
2021-08-19−68.3%−73.1%+3.0%
3 best
2020-04-24+158.7%−0.5%+161.9%
2020-04-27+155.2%+0.0%+163.1%
2020-04-30+148.4%−1.9%+152.6%

2,513 overlapping windows · 2016-08-112026-09-16 · not cherry-picked

Seasonality · by month iHow this security has tended to do in each calendar month historically — a frequency, never a prediction.

iFor each calendar month, the share of years this security closed higher than the month before, and the average month-over-month return, over ~11 years of its own price history. Cells are shaded by average return. This is historical frequency, not a prediction — no month is a signal.
Jan
60%
+3.1%
n=10
Feb
50%
+0.5%
n=10
Mar
50%
+7.8%
n=10
Apr
20%
−11.9%
n=10
May
70%
+18.6%
n=10
Jun
80%
+10.7%
n=10
Jul
60%
+1.4%
n=10
Aug
80%
+15.4%
n=10
Sep
45%
+0.2%
n=11
Oct
40%
+4.0%
n=10
Nov
60%
+7.7%
n=10
Dec
50%
+1.4%
n=10

Up-frequency and average month-over-month return · historical frequency, not a prediction

Reported insider & political trades

Every Form 4 the people closest to this company have filed with the SEC — plotted against the share price, aggregated by month, and shown with the gap between when each trade happened and when it was disclosed. A public record, not advice.

Share price & reported tradesMonthly open-market valueReporting lag — trade date to filing date2026-092026-082026-072026-062026-052026-042026-032026-022026-012025-122025-112025-102025-092025-08$159$552026-09-10: 1 insider sale, $1.0M — PATEL DINESH V PH D2026-09-09: 1 insider sale, $9.3M — PATEL DINESH V PH D2026-09-08: 1 insider sale, $7.9M — PATEL DINESH V PH D2026-08-11: 1 insider sale, $5.1M — PATEL DINESH V PH D2026-08-10: 1 insider sale, $9.8M — PATEL DINESH V PH D2026-06-23: 1 insider sale, $1.1M — Waddill William D.2026-06-10: 1 insider sale, $969K — Waddill William D.2026-05-29: 1 insider sale, $897K — Waddill William D.2026-05-12: 1 insider sale, $7.5M — PATEL DINESH V PH D2026-05-08: 2 insider sales, $1.1M — Giraudo Bryan …2026-05-07: 2 insider sales, $4.8M — Giraudo Bryan …2026-04-20: 1 insider sale, $185K — Ali Asif2026-03-26: 3 insider sales, $6.7M — Ali Asif, SELICK HAROLD E, MOLINA ARTURO MD2026-03-25: 1 insider sale, $5.5M — PATEL DINESH V PH D2026-03-24: 1 insider sale, $6K — PATEL DINESH V PH D2026-02-17: 1 insider sale, $1.5M — Williams Lewis T2026-02-06: 1 insider sale, $1.7M — Waddill William D.2026-01-27: 4 insider sales, $4.6M — Ali Asif, MOLINA ARTURO MD, PATEL DINESH V PH D …2026-01-26: 3 insider sales, $2.5M — PATEL DINESH V PH D, MOLINA ARTURO MD …2026-01-23: 2 insider sales, $2.7M — PATEL DINESH V PH D, MOLINA ARTURO MD2026-01-20: 3 insider sales, $4.3M — PATEL DINESH V PH D, MOLINA ARTURO MD, Ali Asif2025-11-17: 1 insider sale, $230K — MOLINA ARTURO MD2025-10-10: 2 insider sales, $979K — Waddill William D. …2025-09-22: 1 insider sale, $257K — Waddill William D.2025-08-27: 1 insider sale, $237K — Waddill William D.2025-08: 1 open-market sale, $237K2025-09: 1 open-market sale, $257K2025-10: 2 open-market sales, $979K2025-11: 1 open-market sale, $230K2026-01: 12 open-market sales, $14.1M2026-02: 2 open-market sales, $3.2M2026-03: 5 open-market sales, $12.2M2026-04: 1 open-market sale, $185K2026-05: 6 open-market sales, $14.3M2026-06: 2 open-market sales, $2.0M2026-08: 2 open-market sales, $14.9M2026-09: 3 open-market sales, $18.2M↑ buys↓ salesdirector PATEL DINESH V PH D — Sale on 2026-09-10, filed same daydirector PATEL DINESH V PH D — Sale on 2026-09-09, filed 1 day after the tradedirector PATEL DINESH V PH D — Sale on 2026-09-08, filed 2 days after the tradedirector PATEL DINESH V PH D — Sale on 2026-08-11, filed 1 day after the tradedirector PATEL DINESH V PH D — Sale on 2026-08-10, filed 2 days after the tradedirector Waddill William D. — Sale on 2026-06-23, filed 2 days after the tradedirector Waddill William D. — Sale on 2026-06-10, filed 1 day after the tradedirector Waddill William D. — Sale on 2026-05-29, filed 3 days after the tradedirector PATEL DINESH V PH D — Sale on 2026-05-12, filed same daydirector Giraudo Bryan — Sale on 2026-05-08, filed 3 days after the tradedirector Giraudo Bryan — Sale on 2026-05-08, filed 3 days after the tradedirector Giraudo Bryan — Sale on 2026-05-07, filed 4 days after the tradedirector Giraudo Bryan — Sale on 2026-05-07, filed 4 days after the tradeofficer Ali Asif — Sale on 2026-04-20, filed 1 day after the tradeofficer Ali Asif — Sale on 2026-03-26, filed 1 day after the tradedirector SELICK HAROLD E — Sale on 2026-03-26, filed 1 day after the tradeofficer MOLINA ARTURO MD — Sale on 2026-03-26, filed 1 day after the tradedirector PATEL DINESH V PH D — Sale on 2026-03-25, filed same daydirector PATEL DINESH V PH D — Sale on 2026-03-24, filed 1 day after the tradedirector Williams Lewis T — Sale on 2026-02-17, filed 1 day after the tradedirector Waddill William D. — Sale on 2026-02-06, filed same dayofficer Ali Asif — Sale on 2026-01-27, filed same dayofficer Ali Asif — Sale on 2026-01-27, filed same dayofficer MOLINA ARTURO MD — Sale on 2026-01-27, filed same daydirector PATEL DINESH V PH D — Sale on 2026-01-27, filed same daydirector PATEL DINESH V PH D — Sale on 2026-01-26, filed 1 day after the tradedirector PATEL DINESH V PH D — Sale on 2026-01-26, filed 1 day after the tradeofficer MOLINA ARTURO MD — Sale on 2026-01-26, filed 1 day after the tradedirector PATEL DINESH V PH D — Sale on 2026-01-23, filed 4 days after the tradeofficer MOLINA ARTURO MD — Sale on 2026-01-23, filed 4 days after the tradedirector PATEL DINESH V PH D — Sale on 2026-01-20, filed 1 day after the tradeofficer MOLINA ARTURO MD — Sale on 2026-01-20, filed 1 day after the tradeofficer Ali Asif — Sale on 2026-01-20, filed 1 day after the tradeofficer MOLINA ARTURO MD — Sale on 2025-11-17, filed 2 days after the tradedirector Waddill William D. — Sale on 2025-10-10, filed 4 days after the tradedirector Waddill William D. — Sale on 2025-10-10, filed 4 days after the tradedirector Waddill William D. — Sale on 2025-09-22, filed 2 days after the tradedirector Waddill William D. — Sale on 2025-08-27, filed 2 days after the trade
DatePersonRoleActionShares @ priceValueOwnership Δvs S&P 1mvs S&P 6mOwned afterFiling
2026-09-10PATEL DINESH V PH DdirectorSale7,278 @ $144.10$1.0M−1.4% of holdingnot yet — horizon still opennot yet — horizon still open522,968Form 4 · filed same day
2026-09-09PATEL DINESH V PH DdirectorSale63,548 @ $146.18$9.3M−10.8% of holdingnot yet — horizon still opennot yet — horizon still open522,968Form 4 · filed 1 day after the trade
2026-09-08PATEL DINESH V PH DdirectorSale54,174 @ $145.87$7.9M−9.4% of holdingnot yet — horizon still opennot yet — horizon still open522,968Form 4 · filed 2 days after the trade
2026-08-11PATEL DINESH V PH DdirectorSale34,239 @ $148.52$5.1M−6.1% of holding−0.5%not yet — horizon still open523,478Form 4 · filed 1 day after the trade
2026-08-10PATEL DINESH V PH DdirectorSale65,761 @ $149.11$9.8M−11.2% of holding−1.9%not yet — horizon still open523,478Form 4 · filed 2 days after the trade
2026-06-23Waddill William D.directorSale9,000 @ $117.94$1.1M−53.5% of holding+13.2%not yet — horizon still open7,825Form 4 · filed 2 days after the trade
2026-06-10Waddill William D.directorSale9,000 @ $107.68$969K−53.5% of holding+19.3%not yet — horizon still open7,825Form 4 · filed 1 day after the trade
2026-05-29Waddill William D.directorSale9,000 @ $99.64$897K−53.5% of holding+24.2%not yet — horizon still open7,825Form 4 · filed 3 days after the trade
2026-05-12PATEL DINESH V PH DdirectorSale75,000 @ $100.12$7.5M−12.5% of holding+9.9%not yet — horizon still open523,478Form 4 · filed same day
2026-05-08Giraudo BryandirectorSale6,000 @ $100.00$600K−100.0% of holding+6.6%not yet — horizon still open0Form 4 · filed 3 days after the trade
2026-05-08Giraudo BryandirectorSale5,130 @ $100.00$513K−28.8% of holding+6.6%not yet — horizon still open12,695Form 4 · filed 3 days after the trade
2026-05-07Giraudo BryandirectorSale36,000 @ $100.14$3.6M−56.4% of holding−1.9%not yet — horizon still open27,825Form 4 · filed 4 days after the trade
2026-05-07Giraudo BryandirectorSale12,000 @ $100.07$1.2M−66.7% of holding−1.9%not yet — horizon still open6,000Form 4 · filed 4 days after the trade
2026-04-20Ali AsifofficerSale1,750 @ $105.47$185K−2.9% of holding−10.3%not yet — horizon still open59,003Form 4 · filed 1 day after the trade
2026-03-26Ali AsifofficerSale24,765 @ $104.24$2.6M−29.0% of holding−14.4%not yet — horizon still open60,753Form 4 · filed 1 day after the trade
2026-03-26SELICK HAROLD EdirectorSale24,000 @ $105.00$2.5M−28.3% of holding−14.4%not yet — horizon still open60,845Form 4 · filed 1 day after the trade
2026-03-26MOLINA ARTURO MDofficerSale15,000 @ $104.79$1.6M−15.1% of holding−14.4%not yet — horizon still open84,115Form 4 · filed 1 day after the trade
2026-03-25PATEL DINESH V PH DdirectorSale54,641 @ $101.00$5.5M−9.4% of holding−12.8%not yet — horizon still open524,938Form 4 · filed same day
2026-03-24PATEL DINESH V PH DdirectorSale59 @ $101.00$6K−0.0% of holding−6.2%not yet — horizon still open524,938Form 4 · filed 1 day after the trade
2026-02-17Williams Lewis TdirectorSale18,000 @ $82.42$1.5M−69.7% of holding+20.9%+77.8%7,825Form 4 · filed 1 day after the trade
2026-02-06Waddill William D.directorSale20,000 @ $83.68$1.7M−71.9% of holding+16.8%+65.0%7,825Form 4 · filed same day
2026-01-27Ali AsifofficerSale28,000 @ $83.13$2.3M−26.3% of holding+7.3%+54.6%78,523Form 4 · filed same day
2026-01-27Ali AsifofficerSale18,203 @ $83.14$1.5M−23.2% of holding+7.3%+54.6%60,320Form 4 · filed same day
2026-01-27MOLINA ARTURO MDofficerSale5,000 @ $82.00$410K−5.6% of holding+7.3%+54.6%84,115Form 4 · filed same day
2026-01-27PATEL DINESH V PH DdirectorSale4,068 @ $83.19$338K−0.7% of holding+7.3%+54.6%574,505Form 4 · filed same day
2026-01-26PATEL DINESH V PH DdirectorSale14,205 @ $84.05$1.2M−2.4% of holding+5.8%+58.8%574,505Form 4 · filed 1 day after the trade
2026-01-26PATEL DINESH V PH DdirectorSale10,685 @ $84.00$898K−1.8% of holding+5.8%+58.8%574,505Form 4 · filed 1 day after the trade
2026-01-26MOLINA ARTURO MDofficerSale5,000 @ $82.28$411K−5.6% of holding+5.8%+58.8%84,115Form 4 · filed 1 day after the trade
2026-01-23PATEL DINESH V PH DdirectorSale19,315 @ $84.59$1.6M−3.3% of holding+5.4%+55.3%574,505Form 4 · filed 4 days after the trade
2026-01-23MOLINA ARTURO MDofficerSale13,151 @ $82.42$1.1M−13.5% of holding+5.4%+55.3%84,115Form 4 · filed 4 days after the trade
2026-01-20PATEL DINESH V PH DdirectorSale34,438 @ $82.48$2.8M−5.6% of holding−1.4%+51.5%580,505Form 4 · filed 1 day after the trade
2026-01-20MOLINA ARTURO MDofficerSale9,514 @ $82.48$785K−8.9% of holding−1.4%+51.5%97,266Form 4 · filed 1 day after the trade
2026-01-20Ali AsifofficerSale8,588 @ $82.48$708K−9.9% of holding−1.4%+51.5%78,077Form 4 · filed 1 day after the trade
2025-11-17MOLINA ARTURO MDofficerSale2,712 @ $84.77$230K−3.2% of holding+4.5%+7.0%81,180Form 4 · filed 2 days after the trade
2025-10-10Waddill William D.directorSale8,000 @ $87.81$702K−60.9% of holding−8.7%+13.4%5,130Form 4 · filed 4 days after the trade
2025-10-10Waddill William D.directorSale4,000 @ $69.25$277K−23.4% of holding−8.7%+13.4%13,130Form 4 · filed 4 days after the trade
2025-09-22Waddill William D.directorSale4,000 @ $64.25$257K−43.8% of holding+15.6%+57.1%5,130Form 4 · filed 2 days after the trade
2025-08-27Waddill William D.directorSale4,000 @ $59.25$237K−30.5% of holding+7.1%+43.2%9,130Form 4 · filed 2 days after the trade
2025-07-25PATEL DINESH V PH DdirectorSale10,415 @ $54.78$571K−2.0% of holding+2.3%+39.9%520,603Form 4 · filed 3 days after the trade
2025-07-23PATEL DINESH V PH DdirectorSale17,520 @ $54.79$960K−3.2% of holding+3.2%+47.2%531,018Form 4 · filed same day
2025-07-22PATEL DINESH V PH DdirectorSale22,065 @ $55.05$1.2M−3.9% of holding+0.8%+42.9%548,538Form 4 · filed 1 day after the trade
2025-07-21PATEL DINESH V PH DdirectorSale12,859 @ $54.86$705K−2.2% of holding+0.1%+42.7%570,603Form 4 · filed 2 days after the trade
2025-06-10MOLINA ARTURO MDofficerSale10,000 @ $57.03$570K−10.7% of holding−9.7%+43.2%83,892Form 4 · filed 1 day after the trade
2025-06-09MOLINA ARTURO MDofficerSale10,000 @ $55.51$555K−10.7% of holding−9.8%+47.4%83,892Form 4 · filed 2 days after the trade
2025-04-22Ali AsifofficerSale1,756 @ $46.00$81K−2.8% of holding−10.6%+35.5%61,065Form 4 · filed 1 day after the trade
2025-03-17Waddill William D.directorSale4,000 @ $54.25$217K−23.4% of holding−6.5%−6.5%13,130Form 4 · filed 2 days after the trade
2025-03-13MOLINA ARTURO MDofficerSale30,514 @ $55.74$1.7M−26.7% of holding−19.5%−12.7%83,892Form 4 · filed 1 day after the trade
2025-03-12Ali AsifofficerSale24,903 @ $58.73$1.5M−28.4% of holding−23.2%−14.9%62,821Form 4 · filed 2 days after the trade
2025-02-19PATEL DINESH V PH DdirectorSale5,359 @ $38.18$205K−1.0% of holding+45.4%+41.2%540,260Form 4 · filed 1 day after the trade
2025-01-16Ali AsifofficerSale1,317 @ $0.00$0−2.0% of holding−0.0%+44.2%65,422Form 4 · filed 1 day after the trade
2025-01-16MOLINA ARTURO MDofficerSale3,252 @ $0.00$0−3.7% of holding−0.0%+44.2%83,892Form 4 · filed 1 day after the trade
2025-01-16MOLINA ARTURO MDofficerSale388 @ $0.00$0−0.4% of holding−0.0%+44.2%87,144Form 4 · filed 1 day after the trade
2025-01-16Ali AsifofficerSale2,601 @ $0.00$0−4.0% of holding−0.0%+44.2%62,821Form 4 · filed 1 day after the trade

The vs-S&P columns are a labeled look-back on what the stock did after each filing, measured against the index over the same window. Descriptive history, not a claim about the person or a reason to trade.

119 award / exercise / gift records — not counted as purchases

Awards, option exercises, gifts and tax-withholding disposals are shown separately and never counted as open-market purchases or sales — they carry no conviction information.

DatePersonRoleActionSharesOwned afterFiling
2026-09-10PATEL DINESH V PH DdirectorOption exercise7,278530,246Form 4
2026-09-10PATEL DINESH V PH DdirectorOption exercise7,2780Form 4
2026-09-09PATEL DINESH V PH DdirectorOption exercise63,548586,516Form 4
2026-09-09PATEL DINESH V PH DdirectorOption exercise63,5487,278Form 4
2026-09-08PATEL DINESH V PH DdirectorOption exercise54,174577,142Form 4
2026-09-08PATEL DINESH V PH DdirectorOption exercise54,17470,826Form 4
2026-09-03PATEL DINESH V PH DdirectorGift510522,968Form 4
2026-08-11PATEL DINESH V PH DdirectorOption exercise34,239557,717Form 4
2026-08-11PATEL DINESH V PH DdirectorOption exercise34,239125,000Form 4
2026-08-10PATEL DINESH V PH DdirectorOption exercise65,761589,239Form 4
2026-08-10PATEL DINESH V PH DdirectorOption exercise65,761159,239Form 4
2026-06-23Waddill William D.directorOption exercise9,00016,825Form 4
2026-06-23Waddill William D.directorOption exercise9,0000Form 4
2026-06-10Waddill William D.directorOption exercise6,00016,825Form 4
2026-06-10Waddill William D.directorOption exercise3,00010,825Form 4
2026-06-10Waddill William D.directorOption exercise3,0000Form 4
2026-06-10Waddill William D.directorOption exercise6,0009,000Form 4
2026-05-29Waddill William D.directorOption exercise9,00016,825Form 4
2026-05-29Waddill William D.directorOption exercise9,0003,000Form 4
2026-05-12PATEL DINESH V PH DdirectorOption exercise75,000598,478Form 4
2026-05-12PATEL DINESH V PH DdirectorOption exercise75,000225,000Form 4
2026-05-07Giraudo BryandirectorOption exercise24,00031,825Form 4
2026-05-07Giraudo BryandirectorOption exercise12,00043,825Form 4
2026-05-07Giraudo BryandirectorOption exercise12,0000Form 4
2026-05-07Giraudo BryandirectorOption exercise24,0000Form 4
2026-04-23PATEL DINESH V PH DdirectorGift1,460523,478Form 4
2026-03-26Ali AsifofficerOption exercise19,50080,253Form 4
2026-03-26SELICK HAROLD EdirectorOption exercise24,00084,845Form 4
2026-03-26MOLINA ARTURO MDofficerOption exercise15,00099,115Form 4
2026-03-26Ali AsifofficerOption exercise5,26585,518Form 4
2026-03-26Ali AsifofficerOption exercise5,26513,282Form 4
2026-03-26Ali AsifofficerOption exercise19,50031,300Form 4
2026-03-26SELICK HAROLD EdirectorOption exercise24,0000Form 4
2026-03-26MOLINA ARTURO MDofficerOption exercise15,00050,971Form 4
2026-03-25PATEL DINESH V PH DdirectorOption exercise54,641579,579Form 4
2026-03-25PATEL DINESH V PH DdirectorOption exercise54,6410Form 4
2026-03-24PATEL DINESH V PH DdirectorOption exercise59524,997Form 4
2026-03-24PATEL DINESH V PH DdirectorOption exercise5954,641Form 4
2026-03-23PATEL DINESH V PH DdirectorGift50,000524,938Form 4
2026-02-17Williams Lewis TdirectorOption exercise18,00025,825Form 4

Source: SEC Form 4 filings. Each row links to its original filing.

Across 2012–2021, stocks where a CEO, C-suite officer, or director had recently made an open-market common-stock purchase ran about +28 bp per month above the universe average (n=34,268 stock-weeks). A historical tendency, not a prediction.

Congressional disclosures

No congressional trades disclosed for this company.

Research tool, not investment advice — historical frequencies, not recommendations. A product of Marovel Technologies LLC. Full terms.