PRAX · TickerCove

PRAXPraxis Precision Medicines, Inc.Healthcare · Biotechnologyas of 2026-09-16

Horizon

Issued 2026-09-16 at $308.99 · now $308.99 (2026-09-16, +0.0% since)

Based on its own history, a month from the 2026-09-16 close, PRAX has typically landed between $212.36 and $453.28 — a range of −31.3% to +46.7% from the issuance price $308.99.

Range of outcomes in historically similar periods — not a price prediction. Ranges are scored publicly on /methodology.

Actual close
Typical path (median)
Middle 50% of outcomes
90% range

1,461 overlapping 1 month windows · 2020-10-16 – 2026-08-17 · basis climatology · forecast (batch). Probability up 53.9% (90% CI 51.7–56.1%, ≈1,408 obs).

The cone is anchored at the 2026-09-16 issuance close ($308.99) — the price the forecast resolves against on 2026-10-15, not the latest close. The drawn path shape is illustrative (bands widen with √t); every labeled number is real — the anchor, the scored batch p90/IQR endpoints, and the typical move.

52-week range$308.99 · 78% of range

$40.45 low$386.33 high

Trailing 52 weeks to 2026-09-16 — factual context, not a signal.

Base rate up · monthiClimatology base rate that a US-listed stock rises over a month, with its 90% CI and ≈1,408 effective observations. Not a call on this stock — we have no evidence its odds differ.

53.9%

90% CI 51.7%–56.1%

Distribution · month iiThe price-anchored range: typical move (median), and the p90 downside/upside — 90% of similar periods stayed inside these. Ranges, not a prediction of direction.

+3.7%

typical move · IQR 30.9%

−31.3%worst (p90)+46.7%best (p90)

Insider convictioniOpen-market common-stock purchases by company insiders in the last 90 days (grants and option exercises excluded). Historical tendency, not advice — detail below.

conviction buys

0 open-market sales

Congress disclosuresiRecent disclosed congressional trades for this company. Purchase clusters (≥2 members buying within 90 days) historically preceded a modestly higher forward return (+32 bp/mo in 2022–2026, +45 bp/mo in 2015–2021) — a descriptive tendency, not a forecast input. Detail below.

0 buys · 0 sells · 0 members

cluster tilt persisted, ~halved after 2021

Where PRAX has typically landed a month from the 2026-09-16 close of $308.99 — the range is history, not a prediction.

now $308.99 (+0.0%)
typical $320.52 (+3.7%)
middle 50% $272.75–$368.3
90% range $212.36–$453.28

Actual 1-month windows behind the coneiEvery overlapping 1-month window in this security's own price history was ranked by realized return; shown are the 3 worst and 3 best of 1,461 windows spanning 2020-10-16 to 2026-09-16. Not cherry-picked — these are the extremes of the full sample. Max drop / max rise are the deepest and highest points reached within each window. See /methodology.

Start	Return	Max drop	Max rise
3 worst
2022-05-16	−82.2%	−84.0%	+0.3%
2022-05-13	−81.4%	−83.1%	+5.8%
2022-05-17	−81.0%	−84.0%	+0.0%
3 best
2025-09-19	+350.1%	+0.0%	+350.1%
2025-09-17	+331.5%	−4.1%	+331.5%
2025-09-18	+287.1%	−6.7%	+320.1%

1,461 overlapping windows · 2020-10-16 – 2026-09-16 · not cherry-picked

Seasonality · by month i

iFor each calendar month, the share of years this security closed higher than the month before, and the average month-over-month return, over ~6 years of its own price history. Cells are shaded by average return. This is historical frequency, not a prediction — no month is a signal.

Jan

50%

+29.8%

n=6

Feb

33%

−16.6%

n=6

Mar

17%

−16.0%

n=6

Apr

17%

−1.7%

n=6

May

50%

−8.7%

n=6

Jun

33%

−8.6%

n=6

Jul

50%

+12.7%

n=6

Aug

50%

+9.0%

n=6

Sep

50%

−0.8%

n=6

Oct

60%

+51.2%

n=5

Nov

67%

+7.3%

n=6

Dec

83%

+20.7%

n=6

Up-frequency and average month-over-month return · historical frequency, not a prediction

Reported insider & political trades

Every Form 4 the people closest to this company have filed with the SEC — plotted against the share price, aggregated by month, and shown with the gap between when each trade happened and when it was disclosed. A public record, not advice.

Date	Person	Role	Action	Shares @ price	Value	Ownership Δ	vs S&P 1m	vs S&P 6m	Owned after	Filing
2026-06-24	DeSimone Jill	director	Sale	2,854 @ $311.91	$890K	−32.4% of holding	+4.5%	not yet — horizon still open	5,961	Form 4 · filed 2 days after the trade
2026-06-24	DeSimone Jill	director	Sale	1,750 @ $310.89	$544K	−16.6% of holding	+4.5%	not yet — horizon still open	8,815	Form 4 · filed 2 days after the trade
2026-06-24	DeSimone Jill	director	Sale	1,279 @ $314.90	$403K	−28.7% of holding	+4.5%	not yet — horizon still open	3,174	Form 4 · filed 2 days after the trade
2026-06-24	DeSimone Jill	director	Sale	1,240 @ $308.24	$382K	−9.7% of holding	+4.5%	not yet — horizon still open	11,564	Form 4 · filed 2 days after the trade
2026-06-24	DeSimone Jill	director	Sale	1,004 @ $312.83	$314K	−16.8% of holding	+4.5%	not yet — horizon still open	4,957	Form 4 · filed 2 days after the trade
2026-06-24	DeSimone Jill	director	Sale	999 @ $309.38	$309K	−8.6% of holding	+4.5%	not yet — horizon still open	10,565	Form 4 · filed 2 days after the trade
2026-06-24	DeSimone Jill	director	Sale	837 @ $315.70	$264K	−26.4% of holding	+4.5%	not yet — horizon still open	2,337	Form 4 · filed 2 days after the trade
2026-06-24	DeSimone Jill	director	Sale	683 @ $306.77	$210K	−5.1% of holding	+4.5%	not yet — horizon still open	12,804	Form 4 · filed 2 days after the trade
2026-06-24	DeSimone Jill	director	Sale	504 @ $313.66	$158K	−10.2% of holding	+4.5%	not yet — horizon still open	4,453	Form 4 · filed 2 days after the trade
2026-06-24	DeSimone Jill	director	Sale	320 @ $305.31	$98K	−2.3% of holding	+4.5%	not yet — horizon still open	13,487	Form 4 · filed 2 days after the trade
2026-06-24	DeSimone Jill	director	Sale	120 @ $303.13	$36K	−0.9% of holding	+4.5%	not yet — horizon still open	13,807	Form 4 · filed 2 days after the trade
2026-06-24	DeSimone Jill	director	Sale	10 @ $301.44	$3K	−0.1% of holding	+4.5%	not yet — horizon still open	13,927	Form 4 · filed 2 days after the trade
2025-11-20	Nemiroff Alex	officer	Sale	13,339 @ $192.53	$2.6M	−30.1% of holding	+65.6%	+98.0%	30,909	Form 4 · filed 1 day after the trade
2025-11-20	Mastrocola Lauren	officer	Sale	11,455 @ $191.96	$2.2M	−47.6% of holding	+65.6%	+98.0%	12,587	Form 4 · filed 1 day after the trade
2025-11-20	Nemiroff Alex	officer	Sale	9,100 @ $194.30	$1.8M	−30.4% of holding	+65.6%	+98.0%	20,832	Form 4 · filed 1 day after the trade
2025-11-20	Mastrocola Lauren	officer	Sale	2,145 @ $192.71	$413K	−17.0% of holding	+65.6%	+98.0%	10,442	Form 4 · filed 1 day after the trade
2025-11-20	Nemiroff Alex	officer	Sale	1,714 @ $190.86	$327K	−3.7% of holding	+65.6%	+98.0%	44,248	Form 4 · filed 1 day after the trade
2025-11-20	Nemiroff Alex	officer	Sale	977 @ $193.23	$189K	−3.2% of holding	+65.6%	+98.0%	29,932	Form 4 · filed 1 day after the trade
2025-10-16	Adage Capital Management, L.P.	tenPercentOwner	Sale	250,000 @ $104.31	$26.1M	+13.6% of holding	+224.0%	+490.2%	2,081,829	Form 4 · filed 1 day after the trade
2025-10-16	Adage Capital Management, L.P.	tenPercentOwner	Sale	27,287 @ $101.00	$2.8M	+1.2% of holding	+224.0%	+490.2%	2,331,829	Form 4 · filed 1 day after the trade
2025-10-16	Adage Capital Management, L.P.	tenPercentOwner	Sale	19,198 @ $140.00	$2.7M	+0.9% of holding	+224.0%	+490.2%	2,060,175	Form 4 · filed 1 day after the trade
2025-10-16	Adage Capital Management, L.P.	tenPercentOwner	Sale	12,600 @ $90.00	$1.1M	+0.5% of holding	+224.0%	+490.2%	2,361,485	Form 4 · filed 1 day after the trade
2025-10-16	Adage Capital Management, L.P.	tenPercentOwner	Sale	1,661 @ $130.10	$216K	+0.1% of holding	+224.0%	+490.2%	2,080,168	Form 4 · filed 1 day after the trade
2025-10-16	Adage Capital Management, L.P.	tenPercentOwner	Sale	1,363 @ $92.03	$125K	+0.1% of holding	+224.0%	+490.2%	2,359,675	Form 4 · filed 1 day after the trade
2025-10-16	Adage Capital Management, L.P.	tenPercentOwner	Sale	487 @ $131.64	$64K	+0.0% of holding	+224.0%	+490.2%	2,079,681	Form 4 · filed 1 day after the trade
2025-10-16	Adage Capital Management, L.P.	tenPercentOwner	Sale	559 @ $100.11	$56K	+0.0% of holding	+224.0%	+490.2%	2,359,116	Form 4 · filed 1 day after the trade
2025-10-16	Adage Capital Management, L.P.	tenPercentOwner	Sale	308 @ $132.19	$41K	+0.0% of holding	+224.0%	+490.2%	2,079,373	Form 4 · filed 1 day after the trade
2025-10-16	Adage Capital Management, L.P.	tenPercentOwner	Sale	447 @ $91.04	$41K	+0.0% of holding	+224.0%	+490.2%	2,361,038	Form 4 · filed 1 day after the trade

The vs-S&P columns are a labeled look-back on what the stock did after each filing, measured against the index over the same window. Descriptive history, not a claim about the person or a reason to trade.

112 award / exercise / gift records — not counted as purchases

Awards, option exercises, gifts and tax-withholding disposals are shown separately and never counted as open-market purchases or sales — they carry no conviction information.

Date	Person	Role	Action	Shares	Owned after	Filing
2026-07-08	Souza Marcio	director	Gift	2,600	0	Form 4
2026-07-08	Souza Marcio	director	Gift	20,521	56,495	Form 4
2026-06-24	DeSimone Jill	director	Option exercise	3,034	13,937	Form 4
2026-06-24	DeSimone Jill	director	Option exercise	8,566	10,903	Form 4
2026-06-24	DeSimone Jill	director	Option exercise	8,566	0	Form 4
2026-06-24	DeSimone Jill	director	Option exercise	3,034	0	Form 4
2026-06-10	Arbuckle Stuart A	director	Award / grant	648	648	Form 4
2026-06-10	Arbuckle Stuart A	director	Award / grant	1,371	2,537	Form 4
2026-06-10	Chodakewitz Jeffrey	director	Award / grant	1,371	1,371	Form 4
2026-06-10	Chodakewitz Jeffrey	director	Award / grant	648	648	Form 4
2026-06-10	Cudkowicz Merit Ester	director	Award / grant	1,371	1,371	Form 4
2026-06-10	Cudkowicz Merit Ester	director	Award / grant	648	648	Form 4
2026-06-10	DeSimone Jill	director	Award / grant	1,371	2,337	Form 4
2026-06-10	DeSimone Jill	director	Award / grant	648	648	Form 4
2026-06-10	KINDLER JEFFREY B	director	Award / grant	1,371	2,537	Form 4
2026-06-10	KINDLER JEFFREY B	director	Award / grant	648	648	Form 4
2026-06-10	MITCHELL DEAN J	director	Award / grant	1,371	18,622	Form 4
2026-06-10	MITCHELL DEAN J	director	Award / grant	648	648	Form 4
2026-06-10	Norden Gregory	director	Award / grant	1,371	1,559	Form 4
2026-06-10	Norden Gregory	director	Award / grant	648	648	Form 4
2026-06-10	YOUNG WILLIAM D	director	Award / grant	1,371	3,269	Form 4
2026-06-10	YOUNG WILLIAM D	director	Award / grant	648	648	Form 4
2026-05-14	Mastrocola Lauren	officer	Award / grant	127	13,573	Form 4
2026-05-14	Souza Marcio	director	Award / grant	126	77,016	Form 4
2026-05-14	Kelly Timothy Edwin	officer	Award / grant	121	31,167	Form 4
2026-05-14	Sniecinski Megan	officer	Award / grant	89	28,664	Form 4
2026-05-14	Nemiroff Alex	officer	Award / grant	78	26,011	Form 4
2026-02-06	Arbuckle Stuart A	director	Award / grant	224	224	Form 4
2026-02-06	Arbuckle Stuart A	director	Award / grant	688	688	Form 4
2026-02-06	Arbuckle Stuart A	director	Award / grant	478	1,166	Form 4
2026-02-06	KINDLER JEFFREY B	director	Award / grant	688	688	Form 4
2026-02-06	KINDLER JEFFREY B	director	Award / grant	478	1,166	Form 4
2026-02-06	KINDLER JEFFREY B	director	Award / grant	224	224	Form 4
2026-01-12	Kelly Timothy Edwin	officer	Withheld for tax	943	31,046	Form 4
2026-01-12	Sniecinski Megan	officer	Withheld for tax	885	28,530	Form 4
2026-01-12	Nemiroff Alex	officer	Withheld for tax	768	25,933	Form 4
2026-01-12	Mastrocola Lauren	officer	Withheld for tax	344	13,446	Form 4
2026-01-10	Souza Marcio	director	Withheld for tax	4,252	76,890	Form 4
2026-01-10	Kelly Timothy Edwin	officer	Withheld for tax	1,335	31,989	Form 4
2026-01-10	Sniecinski Megan	officer	Withheld for tax	1,087	29,415	Form 4

Source: SEC Form 4 filings. Each row links to its original filing.

Across 2012–2021, stocks where a CEO, C-suite officer, or director had recently made an open-market common-stock purchase ran about +28 bp per month above the universe average (n=34,268 stock-weeks). A historical tendency, not a prediction.

Congressional disclosures

No congressional trades disclosed for this company.

Resolves in i

28d remaining

2026-09-173% elapsed2026-10-15

Logged immutably 2026-09-17; scored automatically on 2026-10-15 — no edits, ever.

Earnings & context analysis

These panels are being prepared. They are generated by multiple language models, checked, and stored before display — never written live for a page view. Until a model panel has been generated and reviewed for a company, nothing is shown here, honestly, rather than a placeholder.

Calibration i

Every forecast is logged when made and scored when the month is up. The record is shown from the day it starts — young and honest.

How scoring works →

Research tool, not investment advice — historical frequencies, not recommendations. A product of Marovel Technologies LLC. Full terms.

Seasonality · by month iHow this security has tended to do in each calendar month historically — a frequency, never a prediction.

Reported insider & political trades

Congressional disclosures

Seasonality · by month i