Issued 2026-09-25 at $2.59 · now $2.59 (2026-09-25, +0.0% since)
Based on its own history, a month from the 2026-09-25 close, PEPG has typically landed between $1.39 and $4.23 — a range of −46.3% to +63.3% from the issuance price $2.59.
- Actual close
- Typical path (median)
- Middle 50% of outcomes
- 90% range
1,077 overlapping 1 month windows · 2022-05-06 – 2026-08-26 · basis climatology · forecast (batch). Base rate up 53.7% (90% CI 51.5–55.9%, ≈1,391 obs). Not a call on this stock — we have no evidence its odds differ.
The cone is anchored at the 2026-09-25 issuance close ($2.59) — the price the forecast resolves against on 2026-10-26, not the latest close. The drawn path shape is illustrative (bands widen with √t); every labeled number is real — the anchor, the scored batch p90/IQR endpoints, and the typical move.
Where PEPG has typically landed a month from the 2026-09-25 close of $2.59 — the range is history, not a prediction.
- now $2.59 (+0.0%)
- typicalThe typical outcome — half of similar past periods did better and half did worse (not an average, so a few wild periods don't skew it). $2.57 (-0.6%)
- middle 50%The central range of outcomes — half of similar past periods landed inside it, a quarter finished above, a quarter below. $2.12–$3.02
- 90% rangeA nine-in-ten range — in about nine of every ten similar past periods the outcome stayed within these bounds. $1.39–$4.23
| Start | Return | Max drop | Max rise |
|---|---|---|---|
| 3 worst | |||
| 2026-03-04 | −74.4% | −74.4% | +0.0% |
| 2026-03-11 | −73.9% | −74.4% | +0.0% |
| 2026-03-10 | −73.9% | −73.9% | +2.1% |
| 3 best | |||
| 2025-09-03 | +331.1% | +0.0% | +331.1% |
| 2025-09-02 | +323.3% | −0.8% | +323.3% |
| 2025-08-29 | +306.0% | +0.0% | +337.1% |
1,077 overlapping windows · 2022-05-06 – 2026-09-25 · not cherry-picked
Pending catalysts
- March 2027 — Trial primary completion: Phase 2 primary completion: A Clinical Study of PGN-EDODM1 in People With Myotonic Dystrophy Type 1 (source, as of 2026-08-14)
- January 2029 — Trial primary completion: Phase 2 primary completion: An Open-Label Extension Study of PGN-EDODM1 in People With Myotonic Dystrophy Type 1 (FREEDOM-OLE) (source, as of 2026-08-14)
Public, scheduled events — dated attention, not a prediction of the outcome. See the FDA catalysts page for the historical base rate.
Seasonality · by month iHow this security has tended to do in each calendar month historically — a frequency, never a prediction.
iFor each calendar month, the share of years this security closed higher than the month before, and the average month-over-month return, over ~5 years of its own price history. Cells are shaded by average return. This is historical frequency, not a prediction — no month is a signal.Up-frequency and average month-over-month return · historical frequency, not a prediction
Reported insider & political trades
Every Form 4 the people closest to this company have filed with the SEC — plotted against the share price, aggregated by month, and shown with the gap between when each trade happened and when it was disclosed. A public record, not advice.
| Date | Person | Role | Action | Shares @ price | Value | Ownership Δ | vs S&P 1m | vs S&P 6m | Owned after | Filing |
|---|---|---|---|---|---|---|---|---|---|---|
| 2026-05-21 | Kasraian Kasra | officer | Sale | 1,233 @ $1.41 | $2K | −2.4% of holding | +19.2% | not yet — horizon still open | 50,074 | Form 4 · filed 5 days after the trade |
| 2026-03-04 | McArthur James G | director | Sale | 5,144 @ $6.23 | $32K | −1.7% of holding | −70.4% | −65.2% | 296,457 | Form 4 · filed 2 days after the trade |
| 2026-03-04 | Donnelly Noel | officer | Sale | 2,032 @ $6.23 | $13K | −1.8% of holding | −70.4% | −65.2% | 111,655 | Form 4 · filed 2 days after the trade |
| 2026-03-04 | STRECK PAUL | officer | Sale | 1,832 @ $6.23 | $11K | −2.3% of holding | −70.4% | −65.2% | 76,273 | Form 4 · filed 2 days after the trade |
| 2026-03-04 | McArthur James G | director | Sale | 131 @ $6.33 | $829 | −0.0% of holding | −70.4% | −65.2% | 296,326 | Form 4 · filed 2 days after the trade |
| 2026-03-04 | Donnelly Noel | officer | Sale | 52 @ $6.33 | $329 | −0.0% of holding | −70.4% | −65.2% | 111,603 | Form 4 · filed 2 days after the trade |
| 2026-03-04 | STRECK PAUL | officer | Sale | 47 @ $6.29 | $296 | −0.1% of holding | −70.4% | −65.2% | 76,226 | Form 4 · filed 2 days after the trade |
| 2025-09-30 | Oxford Science Enterprises plc | other | Purchase | 200,000 @ $3.20 | $640K | +4.2% of holding | −5.6% | −61.3% | 4,955,388 | Form 4 · filed 1 day after the trade |
| 2025-09-26 | RA CAPITAL MANAGEMENT, L.P. | director | Purchase | 9,375,000 @ $3.20 | $30.0M | +102.1% of holding | +3.6% | −12.6% | 18,554,273 | Form 4 · filed 4 days after the trade |
| 2025-05-30 | STRECK PAUL | officer | Purchase | 8,375 @ $1.24 | $10K | +43.1% of holding | −30.4% | +280.5% | 27,805 | Form 4 · filed 3 days after the trade |
| 2025-04-17 | McArthur James G | director | Purchase | 10,000 @ $1.35 | $14K | +9.6% of holding | −1.0% | +243.9% | 113,913 | Form 4 · filed 5 days after the trade |
| 2025-04-08 | McArthur James G | director | Purchase | 41,500 @ $1.15 | $48K | +66.5% of holding | +40.2% | +367.0% | 103,913 | Form 4 · filed 1 day after the trade |
| 2025-02-26 | Donnelly Noel | officer | Sale | 1,527 @ $1.68 | $3K | −47.7% of holding | +9.6% | −28.4% | 1,673 | Form 4 · filed same day |
| 2025-02-26 | DeLena Mary Beth | officer | Sale | 1,432 @ $1.68 | $2K | −47.7% of holding | +9.6% | −28.4% | 1,568 | Form 4 · filed same day |
| 2024-07-25 | Mellion Michelle L | officer | Sale | 7,571 @ $18.06 | $137K | −100.0% of holding | −50.7% | −101.7% | 0 | Form 4 · filed 1 day after the trade |
| 2024-07-24 | Mellion Michelle L | officer | Sale | 201 @ $18.01 | $4K | −100.0% of holding | −47.5% | −102.0% | 0 | Form 4 · filed 2 days after the trade |
| 2024-07-18 | Mellion Michelle L | officer | Sale | 12,625 @ $18.20 | $230K | −100.0% of holding | −43.5% | −95.0% | 0 | Form 4 · filed 1 day after the trade |
| 2024-07-16 | Mellion Michelle L | officer | Sale | 5,901 @ $18.00 | $106K | −100.0% of holding | −50.0% | −91.2% | 0 | Form 4 · filed same day |
| 2024-07-12 | Mellion Michelle L | officer | Sale | 3,288 @ $18.04 | $59K | −100.0% of holding | −44.0% | −87.9% | 0 | Form 4 · filed 4 days after the trade |
| 2024-07-02 | Mellion Michelle L | officer | Sale | 37 @ $18.07 | $669 | −100.0% of holding | −37.2% | −84.2% | 0 | Form 4 · filed 1 day after the trade |
| 2024-07-01 | Mellion Michelle L | officer | Sale | 875 @ $18.01 | $16K | −100.0% of holding | −37.2% | −87.2% | 0 | Form 4 · filed 2 days after the trade |
| 2024-06-24 | Mellion Michelle L | officer | Sale | 9,260 @ $18.19 | $168K | −100.0% of holding | −1.3% | −89.3% | 0 | Form 4 · filed 2 days after the trade |
| 2024-06-12 | Mellion Michelle L | officer | Sale | 1,086 @ $18.06 | $20K | −100.0% of holding | −10.7% | −83.3% | 0 | Form 4 · filed 1 day after the trade |
| 2024-06-11 | Mellion Michelle L | officer | Sale | 500 @ $18.04 | $9K | −100.0% of holding | −10.7% | −84.2% | 0 | Form 4 · filed 2 days after the trade |
| 2024-06-06 | Mellion Michelle L | officer | Sale | 1,411 @ $18.00 | $25K | −100.0% of holding | −4.6% | −81.7% | 0 | Form 4 · filed 1 day after the trade |
| 2024-06-05 | Mellion Michelle L | officer | Sale | 7,245 @ $18.09 | $131K | −100.0% of holding | −11.7% | −81.2% | 0 | Form 4 · filed 2 days after the trade |
| 2024-05-17 | Svenstrup Niels | officer | Sale | 10,000 @ $13.41 | $134K | −100.0% of holding | +20.7% | −80.0% | 0 | Form 4 · filed same day |
The vs-S&P columns are a labeled look-back on what the stock did after each filing, measured against the index over the same window. Descriptive history, not a claim about the person or a reason to trade.
97 award / exercise / gift records — not counted as purchases
Awards, option exercises, gifts and tax-withholding disposals are shown separately and never counted as open-market purchases or sales — they carry no conviction information.
| Date | Person | Role | Action | Shares | Owned after | Filing |
|---|---|---|---|---|---|---|
| 2026-06-18 | KEATING LAURIE | director | Award / grant | 34,000 | 34,000 | Form 4 |
| 2026-06-18 | RA CAPITAL MANAGEMENT, L.P. | director | Award / grant | 34,000 | 34,000 | Form 4 |
| 2026-06-18 | Mayer Howard | director | Award / grant | 34,000 | 34,000 | Form 4 |
| 2026-06-18 | Resnick Joshua | director | Award / grant | 34,000 | 34,000 | Form 4 |
| 2026-06-18 | Wyman Lisa | director | Award / grant | 34,000 | 34,000 | Form 4 |
| 2026-06-18 | Dable Habib J | director | Award / grant | 34,000 | 34,000 | Form 4 |
| 2026-06-18 | Finer Mitchell H. | director | Award / grant | 34,000 | 34,000 | Form 4 |
| 2026-06-18 | HENSON HEIDI | director | Award / grant | 34,000 | 34,000 | Form 4 |
| 2026-03-01 | Vittiglio Joseph | officer | Award / grant | 30,717 | 65,717 | Form 4 |
| 2026-03-01 | McArthur James G | director | Award / grant | 731,250 | 731,250 | Form 4 |
| 2026-03-01 | Vittiglio Joseph | officer | Award / grant | 120,000 | 120,000 | Form 4 |
| 2026-03-01 | Donnelly Noel | officer | Award / grant | 76,793 | 113,687 | Form 4 |
| 2026-03-01 | Donnelly Noel | officer | Award / grant | 300,000 | 300,000 | Form 4 |
| 2026-03-01 | STRECK PAUL | officer | Award / grant | 50,300 | 78,105 | Form 4 |
| 2026-03-01 | STRECK PAUL | officer | Award / grant | 196,500 | 196,500 | Form 4 |
| 2026-03-01 | Kasraian Kasra | officer | Award / grant | 34,557 | 51,307 | Form 4 |
| 2026-03-01 | Kasraian Kasra | officer | Award / grant | 135,000 | 135,000 | Form 4 |
| 2026-03-01 | McArthur James G | director | Award / grant | 187,688 | 301,601 | Form 4 |
| 2025-12-08 | Vittiglio Joseph | officer | Award / grant | 160,000 | 160,000 | Form 4 |
| 2025-12-08 | Vittiglio Joseph | officer | Award / grant | 35,000 | 35,000 | Form 4 |
| 2025-11-04 | Donnelly Noel | officer | Award / grant | 203,339 | 203,339 | Form 4 |
| 2025-11-04 | McArthur James G | director | Disposition | 352,705 | 0 | Form 4 |
| 2025-11-04 | McArthur James G | director | Award / grant | 352,705 | 352,705 | Form 4 |
| 2025-11-04 | McArthur James G | director | Disposition | 40,815 | 0 | Form 4 |
| 2025-11-04 | McArthur James G | director | Award / grant | 40,815 | 40,815 | Form 4 |
| 2025-11-04 | McArthur James G | director | Disposition | 466,095 | 0 | Form 4 |
| 2025-11-04 | McArthur James G | director | Award / grant | 466,095 | 466,095 | Form 4 |
| 2025-11-04 | McArthur James G | director | Disposition | 275,000 | 0 | Form 4 |
| 2025-11-04 | McArthur James G | director | Award / grant | 275,000 | 275,000 | Form 4 |
| 2025-11-04 | McArthur James G | director | Disposition | 300,000 | 0 | Form 4 |
| 2025-11-04 | McArthur James G | director | Award / grant | 300,000 | 300,000 | Form 4 |
| 2025-11-04 | Donnelly Noel | officer | Disposition | 203,339 | 0 | Form 4 |
| 2025-11-04 | Donnelly Noel | officer | Disposition | 169,037 | 0 | Form 4 |
| 2025-11-04 | Donnelly Noel | officer | Award / grant | 169,037 | 169,037 | Form 4 |
| 2025-11-04 | Donnelly Noel | officer | Disposition | 144,000 | 0 | Form 4 |
| 2025-11-04 | Donnelly Noel | officer | Award / grant | 144,000 | 144,000 | Form 4 |
| 2025-11-04 | STRECK PAUL | officer | Disposition | 202,816 | 40,000 | Form 4 |
| 2025-11-04 | STRECK PAUL | officer | Award / grant | 202,816 | 202,816 | Form 4 |
| 2025-11-04 | STRECK PAUL | officer | Disposition | 40,000 | 0 | Form 4 |
| 2025-11-04 | STRECK PAUL | officer | Award / grant | 40,000 | 242,816 | Form 4 |
Source: SEC Form 4 filings. Each row links to its original filing.
Across 2012–2021, stocks where a CEO, C-suite officer, or director had recently made an open-market common-stock purchase ran about +28 bp per month above the universe average (n=34,268 stock-weeks). A historical tendency, not a prediction.
Congressional disclosures
No congressional trades disclosed for this company.
Research tool, not investment advice — historical frequencies, not recommendations. A product of Marovel Technologies LLC. Full terms.