Issued 2026-09-25 at $3.64 · now $3.64 (2026-09-25, +0.0% since)
Based on its own history, a month from the 2026-09-25 close, ANNX has typically landed between $2.37 and $5.14 — a range of −34.9% to +41.3% from the issuance price $3.64.
- Actual close
- Typical path (median)
- Middle 50% of outcomes
- 90% range
1,530 overlapping 1 month windows · 2020-07-24 – 2026-08-26 · basis climatology · forecast (batch). Base rate up 53.7% (90% CI 51.5–55.9%, ≈1,391 obs). Not a call on this stock — we have no evidence its odds differ.
The cone is anchored at the 2026-09-25 issuance close ($3.64) — the price the forecast resolves against on 2026-10-26, not the latest close. The drawn path shape is illustrative (bands widen with √t); every labeled number is real — the anchor, the scored batch p90/IQR endpoints, and the typical move.
Where ANNX has typically landed a month from the 2026-09-25 close of $3.64 — the range is history, not a prediction.
- now $3.64 (+0.0%)
- typicalThe typical outcome — half of similar past periods did better and half did worse (not an average, so a few wild periods don't skew it). $3.63 (-0.4%)
- middle 50%The central range of outcomes — half of similar past periods landed inside it, a quarter finished above, a quarter below. $2.99–$4.26
- 90% rangeA nine-in-ten range — in about nine of every ten similar past periods the outcome stayed within these bounds. $2.37–$5.14
Actual 1-month windows behind the coneiEvery overlapping 1-month window in this security's own price history was ranked by realized return; shown are the 3 worst and 3 best of 1,530 windows spanning 2020-07-24 to 2026-09-25. Not cherry-picked — these are the extremes of the full sample. Max drop / max rise are the deepest and highest points reached within each window. See /methodology.
| Start | Return | Max drop | Max rise |
|---|---|---|---|
| 3 worst | |||
| 2023-04-26 | −60.7% | −60.7% | +19.1% |
| 2021-12-06 | −53.6% | −53.6% | +7.8% |
| 2023-05-16 | −53.5% | −65.2% | +5.5% |
| 3 best | |||
| 2023-12-04 | +102.1% | −0.8% | +104.2% |
| 2023-11-30 | +94.4% | −6.0% | +94.4% |
| 2023-12-01 | +92.7% | +0.0% | +106.8% |
1,530 overlapping windows · 2020-07-24 – 2026-09-25 · not cherry-picked
Pending catalysts
- 2026-10-31 — Trial primary completion: Phase 3 primary completion: A Study Investigating the Efficacy and Safety of Intravitreal (IVT) Injections of Vonaprument (Formerly ANX007) in Participants With Dry Age-Related Macular Degeneration (AMD) With Geographic Atrophy (GA) (source, as of 2026-08-14)
- 2026-12-31 — Trial primary completion: Phase 3 primary completion: An Open Label Clinical Study to Evaluate Tanruprubart (Also Commonly Known as ANX005) in Participants With Guillain-Barré Syndrome (FORWARD Study) (source, as of 2026-08-14)
Public, scheduled events — dated attention, not a prediction of the outcome. See the FDA catalysts page for the historical base rate.
Seasonality · by month iHow this security has tended to do in each calendar month historically — a frequency, never a prediction.
iFor each calendar month, the share of years this security closed higher than the month before, and the average month-over-month return, over ~7 years of its own price history. Cells are shaded by average return. This is historical frequency, not a prediction — no month is a signal.Jan
33%
−3.0%
n=6
Feb
33%
−6.0%
n=6
Mar
17%
−12.5%
n=6
Apr
33%
−5.2%
n=6
May
67%
−1.1%
n=6
Jun
100%
+11.5%
n=6
Jul
33%
+7.4%
n=6
Aug
29%
−2.6%
n=7
Sep
71%
+7.6%
n=7
Oct
33%
−7.1%
n=6
Nov
67%
+9.3%
n=6
Dec
50%
+9.7%
n=6
Up-frequency and average month-over-month return · historical frequency, not a prediction
Reported insider & political trades
Every Form 4 the people closest to this company have filed with the SEC — plotted against the share price, aggregated by month, and shown with the gap between when each trade happened and when it was disclosed. A public record, not advice.
| Date | Person | Role | Action | Shares @ price | Value | Ownership Δ | vs S&P 1m | vs S&P 6m | Owned after | Filing |
|---|---|---|---|---|---|---|---|---|---|---|
| 2026-09-24 | Love Douglas | director | Purchase | 26,065 @ $3.83 | $100K | +7.2% of holding | not yet — horizon still open | not yet — horizon still open | 390,476 | Form 4 · filed 1 day after the trade |
| 2026-05-28 | Satter Muneer A | director | Purchase | 613,497 @ $5.41 | $3.3M | +6.3% of holding | +5.3% | not yet — horizon still open | 10,342,134 | Form 4 · filed 1 day after the trade |
| 2026-05-11 | Carson William H. | director | Purchase | 8,000 @ $5.78 | $46K | +11.4% of holding | −15.0% | not yet — horizon still open | 78,405 | Form 4 · filed 2 days after the trade |
| 2026-04-10 | Carson William H. | director | Purchase | 8,000 @ $6.20 | $50K | +12.8% of holding | −11.7% | not yet — horizon still open | 70,405 | Form 4 · filed 4 days after the trade |
| 2026-03-10 | Carson William H. | director | Purchase | 8,000 @ $5.67 | $45K | +14.7% of holding | +0.3% | −41.3% | 62,405 | Form 4 · filed 2 days after the trade |
| 2026-03-02 | ARTIS DEAN RICHARD | officer | Sale | 5,894 @ $5.43 | $32K | −3.2% of holding | +5.4% | −22.9% | 180,093 | Form 4 · filed 2 days after the trade |
| 2026-03-02 | Dananberg Jamie | officer | Sale | 5,820 @ $5.43 | $32K | −4.5% of holding | +5.4% | −22.9% | 123,582 | Form 4 · filed 2 days after the trade |
| 2026-03-02 | Yednock Ted | officer | Sale | 5,566 @ $5.42 | $30K | −3.5% of holding | +5.4% | −22.9% | 154,161 | Form 4 · filed 2 days after the trade |
| 2026-03-02 | Lew Jennifer | director | Sale | 5,565 @ $5.42 | $30K | −3.2% of holding | +5.4% | −22.9% | 170,700 | Form 4 · filed 2 days after the trade |
| 2026-03-02 | Overdorf Michael | officer | Sale | 4,339 @ $5.42 | $24K | −2.3% of holding | +5.4% | −22.9% | 182,625 | Form 4 · filed 2 days after the trade |
| 2026-02-18 | Yednock Ted | officer | Sale | 7,857 @ $5.11 | $40K | −7.5% of holding | +12.4% | −4.0% | 97,227 | Form 4 · filed 2 days after the trade |
| 2026-02-18 | Lew Jennifer | director | Sale | 7,851 @ $5.11 | $40K | −6.5% of holding | +12.4% | −4.0% | 113,765 | Form 4 · filed 2 days after the trade |
| 2026-02-18 | Overdorf Michael | officer | Sale | 6,225 @ $5.10 | $32K | −4.8% of holding | +12.4% | −4.0% | 124,464 | Form 4 · filed 2 days after the trade |
| 2026-02-18 | Dananberg Jamie | officer | Sale | 5,290 @ $5.10 | $27K | −6.7% of holding | +12.4% | −4.0% | 73,152 | Form 4 · filed 2 days after the trade |
| 2026-02-18 | ARTIS DEAN RICHARD | officer | Sale | 5,290 @ $5.10 | $27K | −4.1% of holding | +12.4% | −4.0% | 123,487 | Form 4 · filed 2 days after the trade |
| 2025-12-30 | Carson William H. | director | Purchase | 4,115 @ $5.02 | $21K | +8.2% of holding | +23.1% | −0.6% | 54,405 | Form 4 · filed 3 days after the trade |
| 2025-12-01 | Choi Jung | director | Purchase | 33,000 @ $4.19 | $138K | ownership Δ n/a | +21.0% | +19.0% | 33,000 | Form 4 · filed 2 days after the trade |
| 2025-12-01 | Carson William H. | director | Purchase | 4,115 @ $4.47 | $18K | +8.9% of holding | +21.0% | +19.0% | 50,290 | Form 4 · filed 2 days after the trade |
| 2025-11-21 | Satter Muneer A | director | Purchase | 422,613 @ $4.28 | $1.8M | +4.5% of holding | +15.0% | +11.7% | 9,728,637 | Form 4 · filed same day |
| 2025-11-20 | Satter Muneer A | director | Purchase | 400,000 @ $4.48 | $1.8M | +4.5% of holding | +16.3% | +13.6% | 9,306,024 | Form 4 · filed 1 day after the trade |
| 2025-11-19 | Satter Muneer A | director | Purchase | 500,000 @ $3.94 | $2.0M | +5.9% of holding | +24.3% | +17.6% | 8,906,024 | Form 4 · filed same day |
| 2025-11-18 | Satter Muneer A | director | Purchase | 500,000 @ $3.18 | $1.6M | +6.3% of holding | +48.1% | +56.8% | 8,406,024 | Form 4 · filed 1 day after the trade |
| 2025-11-17 | Satter Muneer A | director | Purchase | 500,000 @ $2.99 | $1.5M | +6.8% of holding | +61.4% | +54.9% | 7,906,024 | Form 4 · filed 2 days after the trade |
| 2025-10-30 | Carson William H. | director | Purchase | 4,115 @ $3.17 | $13K | +9.8% of holding | +40.9% | +88.0% | 46,175 | Form 4 · filed 1 day after the trade |
| 2025-09-30 | Carson William H. | director | Purchase | 4,115 @ $3.05 | $13K | +10.8% of holding | +1.4% | +76.8% | 42,060 | Form 4 · filed 2 days after the trade |
| 2025-09-02 | Carson William H. | director | Purchase | 4,115 @ $2.09 | $9K | +12.2% of holding | +41.7% | +162.4% | 37,945 | Form 4 · filed 2 days after the trade |
| 2025-07-30 | Carson William H. | director | Purchase | 4,115 @ $2.43 | $10K | +13.8% of holding | −20.4% | +141.7% | 33,830 | Form 4 · filed 2 days after the trade |
| 2025-07-14 | Lew Jennifer | director | Sale | 1,117 @ $2.58 | $3K | −0.9% of holding | −9.4% | +101.1% | 121,616 | Form 4 · filed 2 days after the trade |
| 2025-07-14 | Yednock Ted | officer | Sale | 1,116 @ $2.58 | $3K | −1.1% of holding | −9.4% | +101.1% | 105,084 | Form 4 · filed 2 days after the trade |
| 2025-07-14 | Overdorf Michael | officer | Sale | 853 @ $2.61 | $2K | −0.6% of holding | −9.4% | +101.1% | 130,689 | Form 4 · filed 2 days after the trade |
| 2025-06-30 | Carson William H. | director | Purchase | 4,115 @ $2.46 | $10K | +16.1% of holding | +5.2% | +96.4% | 29,715 | Form 4 · filed 1 day after the trade |
| 2025-02-18 | Yednock Ted | officer | Sale | 8,345 @ $2.91 | $24K | −12.0% of holding | −0.2% | −24.1% | 61,237 | Form 4 · filed 2 days after the trade |
| 2025-02-18 | Lew Jennifer | director | Sale | 6,912 @ $2.92 | $20K | −8.2% of holding | −0.2% | −24.1% | 77,770 | Form 4 · filed 2 days after the trade |
| 2025-02-18 | Overdorf Michael | officer | Sale | 6,618 @ $2.95 | $20K | −7.1% of holding | −0.2% | −24.1% | 86,579 | Form 4 · filed 2 days after the trade |
| 2025-02-18 | ARTIS DEAN RICHARD | officer | Sale | 5,515 @ $2.97 | $16K | −6.2% of holding | −0.2% | −24.1% | 83,814 | Form 4 · filed 2 days after the trade |
| 2025-02-18 | Dananberg Jamie | officer | Sale | 5,521 @ $2.96 | $16K | −14.2% of holding | −0.2% | −24.1% | 33,479 | Form 4 · filed 2 days after the trade |
| 2025-02-13 | Love Douglas | director | Sale | 5,021 @ $2.95 | $15K | −1.4% of holding | −1.7% | −25.1% | 351,554 | Form 4 · filed 5 days after the trade |
| 2025-02-13 | Yednock Ted | officer | Sale | 1,783 @ $2.99 | $5K | −2.5% of holding | −1.7% | −25.1% | 69,582 | Form 4 · filed 5 days after the trade |
| 2025-02-13 | Lew Jennifer | director | Sale | 1,786 @ $2.98 | $5K | −2.1% of holding | −1.7% | −25.1% | 84,682 | Form 4 · filed 5 days after the trade |
| 2025-02-13 | Overdorf Michael | officer | Sale | 1,425 @ $2.99 | $4K | −1.5% of holding | −1.7% | −25.1% | 93,197 | Form 4 · filed 5 days after the trade |
| 2024-12-02 | Carson William H. | director | Purchase | 3,200 @ $5.33 | $17K | +14.3% of holding | +7.2% | −50.5% | 25,600 | Form 4 · filed 2 days after the trade |
| 2024-10-15 | Yednock Ted | officer | Sale | 5,408 @ $7.41 | $40K | −7.0% of holding | −15.1% | −71.8% | 71,365 | Form 4 · filed 2 days after the trade |
| 2024-10-01 | Carson William H. | director | Purchase | 3,200 @ $5.97 | $19K | +16.7% of holding | +21.4% | −65.0% | 22,400 | Form 4 · filed 1 day after the trade |
| 2024-09-19 | Yednock Ted | officer | Sale | 4,500 @ $7.10 | $32K | −100.0% of holding | +3.7% | −63.1% | 0 | Form 4 · filed 1 day after the trade |
| 2024-09-12 | Yednock Ted | officer | Sale | 5,500 @ $6.16 | $34K | −55.0% of holding | +5.7% | −61.2% | 4,500 | Form 4 · filed 4 days after the trade |
| 2024-09-05 | Yednock Ted | officer | Sale | 5,500 @ $5.64 | $31K | −35.5% of holding | +3.5% | −57.8% | 10,000 | Form 4 · filed 1 day after the trade |
| 2024-09-03 | Carson William H. | director | Purchase | 3,200 @ $5.48 | $18K | +20.0% of holding | +15.3% | −54.9% | 19,200 | Form 4 · filed 1 day after the trade |
| 2024-08-29 | Yednock Ted | officer | Sale | 5,500 @ $5.95 | $33K | −26.2% of holding | −3.2% | −62.3% | 15,500 | Form 4 · filed 1 day after the trade |
| 2024-08-01 | Carson William H. | director | Purchase | 3,200 @ $6.24 | $20K | +25.0% of holding | −10.4% | −53.1% | 16,000 | Form 4 · filed 4 days after the trade |
| 2024-07-15 | Yednock Ted | officer | Sale | 1,106 @ $6.02 | $7K | −1.5% of holding | −4.3% | −30.9% | 71,365 | Form 4 · filed 2 days after the trade |
| 2024-07-15 | Lew Jennifer | director | Sale | 1,104 @ $6.03 | $7K | −1.3% of holding | −4.3% | −30.9% | 86,468 | Form 4 · filed 2 days after the trade |
| 2024-07-15 | Overdorf Michael | officer | Sale | 784 @ $6.02 | $5K | −0.8% of holding | −4.3% | −30.9% | 94,622 | Form 4 · filed 2 days after the trade |
| 2024-07-01 | Carson William H. | director | Purchase | 3,200 @ $5.00 | $16K | +33.3% of holding | +25.9% | −7.0% | 12,800 | Form 4 · filed 1 day after the trade |
| 2024-06-03 | Carson William H. | director | Purchase | 3,200 @ $4.83 | $15K | +50.0% of holding | −0.0% | −0.0% | 9,600 | Form 4 · filed 2 days after the trade |
| 2024-05-01 | Carson William H. | director | Purchase | 3,200 @ $4.68 | $15K | +100.0% of holding | −3.7% | +42.1% | 6,400 | Form 4 · filed 2 days after the trade |
| 2024-04-08 | Carson William H. | director | Purchase | 3,200 @ $6.07 | $19K | ownership Δ n/a | −21.5% | −8.7% | 3,200 | Form 4 · filed 2 days after the trade |
| 2024-02-20 | Yednock Ted | officer | Sale | 2,604 @ $5.51 | $14K | −3.5% of holding | +8.4% | +2.2% | 72,471 | Form 4 · filed 1 day after the trade |
| 2024-02-20 | Lew Jennifer | director | Sale | 2,593 @ $5.53 | $14K | −3.1% of holding | +8.4% | +2.2% | 82,058 | Form 4 · filed 1 day after the trade |
| 2024-02-20 | Overdorf Michael | officer | Sale | 1,951 @ $5.48 | $11K | −2.2% of holding | +8.4% | +2.2% | 85,641 | Form 4 · filed 1 day after the trade |
The vs-S&P columns are a labeled look-back on what the stock did after each filing, measured against the index over the same window. Descriptive history, not a claim about the person or a reason to trade.
64 award / exercise / gift records — not counted as purchases
Awards, option exercises, gifts and tax-withholding disposals are shown separately and never counted as open-market purchases or sales — they carry no conviction information.
| Date | Person | Role | Action | Shares | Owned after | Filing |
|---|---|---|---|---|---|---|
| 2026-08-10 | Blumenkranz Mark S. | director | Award / grant | 175,000 | 175,000 | Form 4 |
| 2026-06-11 | Yednock Ted | officer | Option exercise | 30,646 | 184,807 | Form 4 |
| 2026-06-11 | Choi Jung | director | Award / grant | 65,000 | 65,000 | Form 4 |
| 2026-06-11 | Yednock Ted | officer | Option exercise | 30,646 | 0 | Form 4 |
| 2026-06-11 | Carson William H. | director | Award / grant | 65,000 | 65,000 | Form 4 |
| 2026-06-11 | JONES WILLIAM A JR | director | Award / grant | 65,000 | 65,000 | Form 4 |
| 2026-06-11 | Cockroft Bettina M. | director | Award / grant | 65,000 | 65,000 | Form 4 |
| 2026-06-11 | Waddill William D. | director | Award / grant | 65,000 | 65,000 | Form 4 |
| 2026-06-11 | Satter Muneer A | director | Award / grant | 65,000 | 65,000 | Form 4 |
| 2026-02-19 | Dananberg Jamie | officer | Award / grant | 56,250 | 129,402 | Form 4 |
| 2026-02-19 | Lew Jennifer | director | Award / grant | 62,500 | 176,265 | Form 4 |
| 2026-02-19 | Lew Jennifer | director | Award / grant | 250,000 | 250,000 | Form 4 |
| 2026-02-19 | Dananberg Jamie | officer | Award / grant | 225,000 | 225,000 | Form 4 |
| 2026-02-19 | Love Douglas | director | Award / grant | 1,250,000 | 1,250,000 | Form 4 |
| 2026-02-19 | Yednock Ted | officer | Award / grant | 62,500 | 159,727 | Form 4 |
| 2026-02-19 | Yednock Ted | officer | Award / grant | 250,000 | 250,000 | Form 4 |
| 2026-02-19 | ARTIS DEAN RICHARD | officer | Award / grant | 62,500 | 185,987 | Form 4 |
| 2026-02-19 | ARTIS DEAN RICHARD | officer | Award / grant | 250,000 | 250,000 | Form 4 |
| 2026-02-19 | Overdorf Michael | officer | Award / grant | 62,500 | 186,964 | Form 4 |
| 2026-02-19 | Overdorf Michael | officer | Award / grant | 250,000 | 250,000 | Form 4 |
| 2025-06-05 | Choi Jung | director | Award / grant | 55,000 | 55,000 | Form 4 |
| 2025-06-05 | Satter Muneer A | director | Award / grant | 55,000 | 55,000 | Form 4 |
| 2025-06-05 | Waddill William D. | director | Award / grant | 55,000 | 55,000 | Form 4 |
| 2025-06-05 | WIGGANS THOMAS G | director | Award / grant | 55,000 | 55,000 | Form 4 |
| 2025-06-05 | Cockroft Bettina M. | director | Award / grant | 55,000 | 55,000 | Form 4 |
| 2025-06-05 | JONES WILLIAM A JR | director | Award / grant | 55,000 | 55,000 | Form 4 |
| 2025-06-05 | Carson William H. | director | Award / grant | 55,000 | 55,000 | Form 4 |
| 2025-02-27 | Dananberg Jamie | officer | Award / grant | 228,225 | 228,225 | Form 4 |
| 2025-02-27 | Overdorf Michael | officer | Award / grant | 272,575 | 272,575 | Form 4 |
| 2025-02-27 | Love Douglas | director | Award / grant | 1,300,000 | 1,300,000 | Form 4 |
| 2025-02-27 | Yednock Ted | officer | Award / grant | 272,575 | 272,575 | Form 4 |
| 2025-02-27 | Lew Jennifer | director | Award / grant | 272,575 | 272,575 | Form 4 |
| 2025-02-27 | ARTIS DEAN RICHARD | officer | Award / grant | 272,575 | 272,575 | Form 4 |
| 2025-01-09 | JONES WILLIAM A JR | director | Award / grant | 88,000 | 88,000 | Form 4 |
| 2025-01-06 | Love Douglas | director | Option exercise | 37,994 | 356,575 | Form 4 |
| 2025-01-06 | Love Douglas | director | Option exercise | 37,994 | 0 | Form 4 |
| 2024-10-30 | Love Douglas | director | Option exercise | 78,399 | 274,520 | Form 4 |
| 2024-10-30 | Love Douglas | director | Option exercise | 36,050 | 310,570 | Form 4 |
| 2024-10-30 | Love Douglas | director | Option exercise | 78,399 | 0 | Form 4 |
| 2024-10-30 | Love Douglas | director | Option exercise | 36,050 | 0 | Form 4 |
Source: SEC Form 4 filings. Each row links to its original filing.
Across 2012–2021, stocks where a CEO, C-suite officer, or director had recently made an open-market common-stock purchase ran about +28 bp per month above the universe average (n=34,268 stock-weeks). A historical tendency, not a prediction.
Congressional disclosures
No congressional trades disclosed for this company.
Research tool, not investment advice — historical frequencies, not recommendations. A product of Marovel Technologies LLC. Full terms.